Ryan S, Arden G B, Weinstein G W
Department of Clinical Ophthalmology, Institute of Ophthalmology, London, England.
Metab Pediatr Syst Ophthalmol (1985). 1989;12(1-3):69-73.
In this study we show how the Pattern ERG (PERG) can be used to distinguish between optic nerve and retinal disease. Records from eyes with RBN and delayed visual evoked responses are compared with those recorded from the normal fellow eyes. In optic nerve disease there is a selective reduction of the later negative component of the response. PERG's were also recorded from patients with mild diabetic retinopathy. These were divided into three groups on the basis of the delay in their Visual Evoked Potential (VEP). The amplitude of both positive and negative components fall with increasing severity of the disease thus showing that the abnormally long delau in VEP found in some cases is due to retinal disease rather than optic nerve disease.
在本研究中，我们展示了图形视网膜电图（PERG）如何用于区分视神经疾病和视网膜疾病。将视网膜神经节细胞病变（RBN）和视觉诱发电位延迟的眼睛记录与正常对侧眼睛的记录进行比较。在视神经疾病中，反应的后期负向成分有选择性降低。还记录了轻度糖尿病性视网膜病变患者的PERG。根据其视觉诱发电位（VEP）的延迟情况将这些患者分为三组。随着疾病严重程度的增加，正向和负向成分的振幅均下降，这表明在某些情况下发现的VEP异常长时间延迟是由于视网膜疾病而非视神经疾病所致。
