Song H S, Ku W C, Yeh S F
Department of Ophthalmology, Chang Gung Memorial Hospital, at Keelung, Taiwan, R.O.C.
Changgeng Yi Xue Za Zhi. 1995 Jun;18(2):133-9.
Thirteen eyes of optic neuropathy and 13 eyes of maculopathy during Sep. 1990-May 1992 were studied by simultaneous pattern VEP (PVEP) and pattern ERG (PERG) recording. In optic neuropathy, the P100 of PVEP was delayed in 7 eyes (ave. 108.87 msec; normal 94.41 +/- 3.51 msec), absent in 5 eyes, normal in 1 eye. Their PERG showed normal P50 amplitude (either normal or delayed latency) but small or absent N95 in 8 eyes. In maculopathy, the P100 of PVEP was delayed in 2 eyes (ave. 103.59msec), absent in 7 eyes, normal in 4 eyes. However, their PERG showed 12 eyes had small or absent P50. Combined PVEP & PERG test, when compared to PVEP alone, increased the diagnostic value from 57.1% to 100% for optic neuropathy and from 42.9% to 80% for maculopathy in this study. Thus, simultaneous PVEP & PERG recording is highly recommended in evaluation of anterior visual pathway disorders.
1990年9月至1992年5月期间，对13例视神经病变患者的13只眼和13例黄斑病变患者的13只眼进行了同步图形视觉诱发电位（PVEP）和图形视网膜电图（PERG）记录研究。在视神经病变中，PVEP的P100波潜伏期在7只眼中延迟（平均108.87毫秒；正常为94.41±3.51毫秒），5只眼中未引出，1只眼正常。其PERG显示P50波幅正常（潜伏期正常或延迟），但8只眼中N95波幅小或未引出。在黄斑病变中，PVEP的P100波潜伏期在2只眼中延迟（平均103.59毫秒），7只眼中未引出，4只眼正常。然而，其PERG显示12只眼中P50波幅小或未引出。在本研究中，联合PVEP和PERG检查与单独使用PVEP相比，对视神经病变的诊断价值从57.1%提高到100%，对黄斑病变的诊断价值从42.9%提高到80%。因此，在评估前部视觉通路疾病时，强烈建议同时进行PVEP和PERG记录。
