Department of Orthopedic Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310009, China.
Department of Plastic Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310009, China.
PLoS One. 2016 Oct 5;11(10):e0163515. doi: 10.1371/journal.pone.0163515. eCollection 2016.
To enhance surgical exposure, resection of the infrapatellar fat pad (IPFP) is usually a routine procedure in total knee arthroplasty (TKA). However, there is conflicting evidence regarding whether IPFP resection during TKA impairs clinical outcome. We performed a systematic review and meta-analysis to clarify the influence of IPFP resection on primary TKA.
Embase, PubMed, and the Cochrane Library were systematically searched up to August 2016 to identify relevant studies. All clinical studies comparing IPFP resection (IPFP-R) and IPFP preservation (IPFP-P) in patients undergoing primary TKA were obtained. The meta-analysis was performed with Revman 5.3 and STATA 12.0 software. The weighted mean was estimated by using random effects (RE) models with 95% CIs, heterogeneity was assessed using the H statistic and the inconsistency index (I2).
Seven studies involving 2,734 patients (3,258 knees) were included. IPFP resection trended to increase the incidence of postoperative anterior knee pain within 2 months postoperatively, compared with patients in whom the IPFP was preserved (odds ratio [OR]s 2.12[0.95, 4.73], p = 0.07). An increased incidence of anterior knee pain was observed in the IPFP resection group > 12 months postoperatively, but the difference was not significant (OR, 3.69 [0.81, 16.82], p = 0.07). In addition, a trend towards more shortening of the patellar tendon was also observed in the IPFP-R group. No significant results were found regarding postoperative knee function.
These results suggest that preserving the IPFP may be superior to IPFP resection in patients undergoing primary TKA, due to the relatively lower rate of anterior knee pain after short-term follow-up.
为了增强手术显露,切除髌下脂肪垫(IPFP)通常是全膝关节置换术(TKA)的常规程序。然而,关于 TKA 期间切除 IPFP 是否会影响临床结果存在相互矛盾的证据。我们进行了系统评价和荟萃分析,以阐明切除 IPFP 对初次 TKA 的影响。
系统检索了 Embase、PubMed 和 Cochrane 图书馆,以查找截至 2016 年 8 月的相关研究。获取了所有比较初次 TKA 中切除 IPFP(IPFP-R)和保留 IPFP(IPFP-P)的临床研究。使用 Revman 5.3 和 STATA 12.0 软件进行荟萃分析。使用随机效应(RE)模型和 95%CI 估计加权均数,使用 H 统计量和不一致指数(I2)评估异质性。
纳入了 7 项研究,共 2734 名患者(3258 膝)。与保留 IPFP 的患者相比,IPFP 切除术后 2 个月内术后前膝痛的发生率呈上升趋势(优势比[OR]2.12[0.95, 4.73],p = 0.07)。在 IPFP 切除组中,术后 12 个月以上观察到前膝痛的发生率增加,但差异无统计学意义(OR,3.69 [0.81, 16.82],p = 0.07)。此外,在 IPFP-R 组中还观察到髌腱缩短的趋势。术后膝关节功能无显著结果。
这些结果表明,在初次 TKA 患者中,保留 IPFP 可能优于切除 IPFP,因为在短期随访后,前膝痛的发生率相对较低。