Skarka P, Sestáková I
Arch Toxicol Suppl. 1978(1):207-10.
In order to establishe the length of the protective period for which the animals are given food without chemical growth stimulators before slaughter two methods are proposed permitting wide use in sanitary control: 1/ A highly sensitive method of pulse-polarography has been worked out for the estimation of widely used growth stimulator nitrovin residues/ 1.5-bis/5-nitro2-furyl/1.4-pentadiene-3-on amidinohydrazone / and its metabolites. In the tissues of the experimental animals examined were found residues at a level of about 50 ppb. The limit of sensitivity of the procedure used is 10 ppb. 2/ Based upon double-electron reduction of the quinoxaline circle a simple and sufficiently sensitive polarographic method was worked out for the estimation of carbadox residues / quinoxaline-1.4-N-dioxide-2-methylcarbazate/and its main metabolite / quinoxaline-2-carboxylic acid/. With the sensitivity of the method of 0.1 ppm excretion curves were designed and residue levels were determined in tissues of pigs fed up to 56 days of age by feed containing 20 - 50 ppm of carbadox.
为确定动物在屠宰前不使用化学生长刺激剂的饲养保护期时长，提出了两种可广泛应用于卫生控制的方法：1/ 已研发出一种高灵敏度的脉冲极谱法，用于测定广泛使用的生长刺激剂硝呋烯腙残留量/1,5-双（5-硝基-2-呋喃基）-1,4-戊二烯-3-酮脒腙/及其代谢产物。在所检测的实验动物组织中，发现残留量约为50 ppb。所用方法的灵敏度极限为10 ppb。2/ 基于喹喔啉环的双电子还原反应，研发出一种简单且灵敏度足够高的极谱法，用于测定卡巴氧残留量/喹喔啉-1,4-二氧化物-2-甲基氨基脲/及其主要代谢产物/喹喔啉-2-羧酸/。该方法灵敏度为0.1 ppm，据此绘制了排泄曲线，并测定了食用含20 - 50 ppm卡巴氧饲料直至56日龄的猪组织中的残留量。
