Madonna Rosalinda, De Caterina Raffaele, Geng Yong-Jian
The Center for Cardiovascular Biology and Atherosclerosis Research, Department of Internal Medicine, The University of Texas Health Science Center at Houston, Houston, TX, United States; Center of Excellence on Aging, "G. d'Annunzio" University, Chieti, Italy.
Center of Excellence on Aging, "G. d'Annunzio" University, Chieti, Italy; Institute of Cardiology, Department of Neuroscience and Imaging, "G. d'Annunzio" University, Chieti, Italy.
Vascul Pharmacol. 2016 Dec;87:6-9. doi: 10.1016/j.vph.2016.10.002. Epub 2016 Oct 5.
Characterized by progressive elevation of mean pulmonary artery pressure and pulmonary vascular resistance, pulmonary arterial hypertension (PAH) is an important health problem that contributes to right heart failure. Pulmonary arterial remodeling and constriction are two prominent features of PAH. It is a traditional view that increasing pulmonary blood flow and pressure, aerobic exercise does more harm than good to the pulmonary vasculature in PAH. However, recent studies have documented a potential benefit of low-intensity aerobic exercise for PAH patients. Here the current mini-review outlines the evidence and challenges for this additional tool in our armamentarium to combat this ominous disease.
肺动脉高压（PAH）的特征是平均肺动脉压和肺血管阻力逐渐升高，是导致右心衰竭的一个重要健康问题。肺动脉重塑和收缩是PAH的两个突出特征。传统观点认为，在PAH患者中，增加肺血流量和压力，有氧运动对肺血管系统弊大于利。然而，最近的研究证明了低强度有氧运动对PAH患者有潜在益处。本文献综述概述了在我们对抗这种严重疾病的手段中使用这一额外工具的证据和挑战。
