Tournadre Anne, Mathieu Sylvain, Soubrier Martin
Rheumatology Department, CHU Clermont-Ferrand, Clermont-Ferrand, France.
Rheumatology Department, CHU Gabriel Montpied, 58 Rue Montalembert, F-63000 Clermont-Ferrand, France.
Ther Adv Musculoskelet Dis. 2016 Oct;8(5):180-191. doi: 10.1177/1759720X16664306. Epub 2016 Sep 5.
Patients with inflammatory arthritis, such as rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis, have higher rates of cardiovascular mortality. While the increased cardiovascular risk is only explained to some extent, a lot of research is currently conducted to improve our understanding of its pathogenesis, risk stratification, and optimal cardiovascular risk management. This review sought to report epidemiological data pertaining to the cardiovascular disease burden in patients with inflammatory arthritis, underlying mechanisms accounting for excessive cardiovascular risk, along with recommendations regarding risk assessment and management in this patient population.
患有炎性关节炎(如类风湿性关节炎、银屑病关节炎或强直性脊柱炎)的患者心血管疾病死亡率较高。虽然心血管风险增加仅在一定程度上得到了解释,但目前正在进行大量研究,以增进我们对其发病机制、风险分层和最佳心血管风险管理的理解。本综述旨在报告与炎性关节炎患者心血管疾病负担相关的流行病学数据、导致心血管风险过高的潜在机制,以及关于该患者群体风险评估和管理的建议。