Pandey Arvind Kumar, Kumar Pramod, Aithal Srinivas Kodavoor, Kotian Sushma R, Thittamaranahalli Honnegowda, Bangera Hemalatha, Prasad Keerthana, Souza Anne D
Department of Anatomy, Kasturba Medical College, Manipal University, Manipal, India.
King Abdul Aziz Hospital, Ministry of Health, Sakaka, Saudi Arabia.
Anat Cell Biol. 2016 Sep;49(3):184-188. doi: 10.5115/acb.2016.49.3.184. Epub 2016 Sep 29.
The advancement of liposculpturing and fascial flaps in reconstructive surgery has renewed interest in the superficial fascia of abdomen. Its histological and biochemical composition may play a vital role in maintaining strength and elasticity of the fascia. Hence, study of abdominal fascia for the elastic, collagen, and hydroxyproline contents is desirable to understand asymmetrical bulges and skin folds and in improving surgical treatment of obesity. Samples of superficial fascia were collected from of upper and lower abdomen from 21 fresh cadavers (15 males and 6 females). Samples were stained using Verhoeff-Van Gieson stain. Digital images of superficial fascia were analyzed using TissueQuant software. The samples were also subjected to hydroxyproline estimation. The superficial fascia was formed by loosely packed collagen fibers mixed with abundant elastic fibers and adipose tissue. Elastic contents and collagen contents of superficial fascia were significantly more in the upper abdomen than that in the lower abdomen in males. Hydroxyproline content of superficial fascia of upper abdomen was significantly more than that of lower abdomen in both males and females. The elastic, collagen and hydroxyproline contents of superficial fascia of upper abdomen were higher compared to the lower abdomen. This may be a reason for asymmetric bulging over abdomen and more sagging fold of skin in the lower abdomen than in the upper abdomen. This study may therefore be helpful in finding new ways to manage obesity and other body contour deformities.
脂肪雕塑和筋膜瓣在重建手术中的进展重新激发了人们对腹部浅筋膜的兴趣。其组织学和生化组成可能在维持筋膜的强度和弹性方面发挥至关重要的作用。因此，研究腹部筋膜的弹性、胶原蛋白和羟脯氨酸含量，对于理解不对称隆起和皮肤褶皱以及改善肥胖症的手术治疗是有必要的。从21具新鲜尸体（15例男性和6例女性）的上腹部和下腹部采集浅筋膜样本。样本用Verhoeff-Van Gieson染色法染色。使用TissueQuant软件分析浅筋膜的数字图像。样本还进行了羟脯氨酸含量测定。浅筋膜由疏松排列的胶原纤维与丰富的弹性纤维和脂肪组织混合而成。男性上腹部浅筋膜的弹性成分和胶原成分明显多于下腹部。男性和女性上腹部浅筋膜的羟脯氨酸含量均明显高于下腹部。上腹部浅筋膜的弹性、胶原蛋白和羟脯氨酸含量均高于下腹部。这可能是腹部出现不对称隆起以及下腹部皮肤下垂褶皱比上腹部更多的原因。因此，本研究可能有助于找到管理肥胖症和其他身体轮廓畸形的新方法。
