Coronel F, Hortal L, Horcajo P, Naranjo P, del Pozo C, Torrente J, Barrientos A
Rev Clin Esp. 1989 Mar;184(5):225-9.
In treated diabetic patients with terminal renal failure we have examined the complications arising from the dialysis technique used. 55 patients were followed up for 1.279 months. Out of the latter, 24 were on hemodialysis (HD) 33 on continuous ambulatory peritoneal dialysis (CAPD) and 9 on intermittent peritoneal dialysis (IPD). Intraperitoneal insulin in patients on CAPD best controlled glycemia. Antihypertensive therapy was not necessary in 86%, 66%, and 46% of the patients on CAPD, IPD and HD respectively (CAPD vs HD, p less than 0.001). Acute myocardial infarction was more common in patients on HD (33%) (p less than 0.05). 22% of the patients on IPD had limb amputation (IPD vs CAPD-HD, p less than 0.05). The type of dialysis method used does not seem to influence the course of the retinopathy. The neuropathy behaved in a similar manner in those on CAPD and on HD when followed up for two years. Vascular complications were frequent in those on HD with one thrombotic event every 9.7 months/patient and a new vascular access every 7.4 months/patient. Peritonitis was the main complication of CAPD and IPD which was found more frequent in the former and longer hospitalization in the latter. The election of the dialysis technique in diabetic patients can directly influence the glycemia levels and blood pressure reading, as well as heart complications and those due to the method used. However they seem to influence less the neuropathy, retinopathy and peripheral vasculopathy.
在接受治疗的终末期肾衰竭糖尿病患者中,我们研究了所用透析技术引发的并发症。55例患者接受了1279个月的随访。其中,24例接受血液透析(HD),33例接受持续性非卧床腹膜透析(CAPD),9例接受间歇性腹膜透析(IPD)。接受CAPD的患者腹腔内注射胰岛素能最佳地控制血糖。分别有86%、66%和46%接受CAPD、IPD和HD的患者无需进行抗高血压治疗(CAPD与HD相比,p<0.001)。HD患者急性心肌梗死更为常见(33%)(p<0.05)。接受IPD的患者中有22%进行了肢体截肢(IPD与CAPD-HD相比,p<0.05)。所用透析方法的类型似乎不影响视网膜病变的病程。随访两年时,接受CAPD和HD的患者神经病变表现相似。HD患者血管并发症频繁,每位患者每9.7个月发生一次血栓事件,每7.4个月需要建立一次新的血管通路。腹膜炎是CAPD和IPD的主要并发症,前者更为常见,后者住院时间更长。糖尿病患者透析技术的选择可直接影响血糖水平、血压读数以及心脏并发症和所用方法导致的并发症。然而,它们似乎对神经病变、视网膜病变和周围血管病变的影响较小。