米索硝唑用于头颈部癌症的初步临床研究。
A preliminary clinical study in the use of misonidazole in cancer of the head and neck.
作者信息
Sealy R
出版信息
Br J Cancer Suppl. 1978 Jun;3:314-7.
Abstract
The value of misonidazole in advanced head and neck cancer was examined in 3 ways and the preliminary results are reported in a randomized study with large fractions of irradiation, when misonidazole appeared to confer no advantage; whereas in previously (partially) treated patients misonidazole was possibly useful. The combination of hyperbaric oxygen and misonidazole did not appear to be toxic.
摘要
以3种方式研究了甲硝唑在晚期头颈癌中的价值，并在一项使用大剂量照射的随机研究中报告了初步结果，结果显示甲硝唑似乎并无优势；而在先前（部分）接受过治疗的患者中，甲硝唑可能有用。高压氧与甲硝唑联合使用似乎没有毒性。
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