Liang Zhenhu, Gu Yue, Duan Xuejing, Cheng Lei, Liang Shujuan, Tong Yunjie, Li Xiaoli
Yanshan University , Institute of Electrical Engineering, No. 438 Hebei Street, Haigang District, Qinhuangdao 066004, China.
Department of Anesthesia , No. 1 Hospital of Qinhuangdao, No. 258 Wenhua Street, Haigang District, Qinhuangdao 066004, China.
Neurophotonics. 2016 Oct;3(4):045001. doi: 10.1117/1.NPh.3.4.045001. Epub 2016 Oct 5.
Monitoring the changes of cerebral hemodynamics and the state of consciousness during general anesthesia (GA) is clinically important. There is a great need for developing advanced detectors to investigate the physiological processes of the brain during GA. We developed a multichanneled, functional near-infrared spectroscopy (fNIRS) system device and applied it to GA operation monitoring. The cerebral hemodynamic data from the forehead of 11 patients undergoing propofol and sevoflurane anesthesia were analyzed. The concentration changes of oxygenated hemoglobin, deoxygenated hemoglobin, total hemoglobin, and cerebral tissue heart rate were determined from the raw optical information based on the discrete stationary wavelet transform. This custom-made device provides an easy-to-build solution for continuous wave-fNIRS system, with customized specifications. The developed device has a potential value in cerebral monitoring in clinical settings.
在全身麻醉（GA）期间监测脑血流动力学变化和意识状态具有重要的临床意义。迫切需要开发先进的探测器来研究全身麻醉期间大脑的生理过程。我们开发了一种多通道功能近红外光谱（fNIRS）系统设备，并将其应用于全身麻醉手术监测。分析了11例接受丙泊酚和七氟醚麻醉患者前额的脑血流动力学数据。基于离散平稳小波变换，从原始光学信息中确定了氧合血红蛋白、脱氧血红蛋白、总血红蛋白和脑组织心率的浓度变化。这种定制设备为连续波fNIRS系统提供了一种易于构建的解决方案，具有定制的规格。所开发的设备在临床环境中的脑监测方面具有潜在价值。
