Hosang Georgina M, Cardno Alastair G, Freeman Daniel, Ronald Angelica
Psychology Department, Goldsmiths, University of London, London SE14 6NW, UK.
Academic Unit of Psychiatry and Behavioural Sciences, University of Leeds, Leeds Institute of Health Sciences, Charles Thackrah Building, University of Leeds, 101 Clarendon Road, Leeds LS2 9LJ, UK.
J Affect Disord. 2017 Jan 1;207:228-235. doi: 10.1016/j.jad.2016.08.033. Epub 2016 Oct 2.
This study aimed to test the validity of using the Hypomania Checklist-16 [HCL-16] to measure hypomania in a British adolescent community sample. Limited research is available concerning the characterization of hypomania among community adolescent samples, particularly in the UK, despite its potential importance for early intervention policy development.
To explore the structure and characterization of hypomania in a British adolescent nonclinical cohort, over 1400 17 year olds (Mean=17.05 years; SD=0.88) completed the HCL-16 along with measures of different psychological and psychopathological dimensions.
Principal components analysis revealed a 2-component solution for the HCL-16, described as active-elated and irritable/risk-taking. Hypomanic symptoms were significantly correlated with many psychopathological dimensions. There were distinct correlation patterns for the two HCL-16 subscales, with the irritability/risk-taking subscale showing significantly stronger associations with psychotic-like experiences, internalizing and externalizing problems, and reduced life satisfaction relative to the active-elated dimension. Adolescents at 'high-risk' for bipolar disorder reported more psychopathology relative to the comparison group.
Absence of the clinical diagnosis of bipolar disorder in the sample means that the classification of the 'high-risk' group cannot be confirmed.
The structure of the HCL-16 in this UK adolescent sample mirrored that observed in adult and clinical cohorts. The observed links between the HCL-16 and psychopathological dimensions that have been previously associated with both hypomania and bipolar disorder lend support to the HCL-16's validity as a hypomania instrument for adolescents. Better understanding of hypomania prior to adulthood has considerable potential for informing early intervention approaches.
本研究旨在检验使用轻躁狂检查表-16（HCL-16）来测量英国青少年社区样本中的轻躁狂的有效性。尽管轻躁狂对于早期干预政策制定具有潜在重要性，但关于社区青少年样本中轻躁狂特征的研究有限，尤其是在英国。
为了探究英国青少年非临床队列中轻躁狂的结构和特征，1400多名17岁青少年（平均年龄=17.05岁；标准差=0.88）完成了HCL-16以及不同心理和精神病理维度的测量。
主成分分析揭示了HCL-16的一个两成分解决方案，分别描述为活跃-欣快和易怒/冒险。轻躁狂症状与许多精神病理维度显著相关。HCL-16的两个分量表有不同的相关模式，与活跃-欣快维度相比，易怒/冒险分量表与类精神病体验、内化和外化问题以及生活满意度降低的关联显著更强。与对照组相比，双相情感障碍“高风险”青少年报告了更多的精神病理学问题。
样本中缺乏双相情感障碍的临床诊断意味着“高风险组”的分类无法得到证实。
该英国青少年样本中HCL-16的结构与在成人和临床队列中观察到的结构相似。HCL-16与先前与轻躁狂和双相情感障碍相关的精神病理维度之间的观察联系支持了HCL-16作为青少年轻躁狂测量工具的有效性。在成年前更好地理解轻躁狂对于指导早期干预方法具有相当大的潜力。
