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[尸体材料中曲唑酮的测定]

[Determination of trasodone in cadaveric material].

作者信息

Mironova T V

出版信息

Sud Med Ekspert. 1989 Apr-Jun;32(2):34-5.

PMID:2773009
Abstract

Methods of trasodone isolation from cadaveric material by water and acetonitrile at pH-2.0, which may be used in expert practice, were developed. Acetonitrile method is recommended for everyday practice as it allows one to isolate about 60% of trasodone and to obtain extracts with lower content of extractive substances. Detection limit in case of trasodone isolation by acidified water is 50 micrograms in 25 g of the liver and by acetonitrile--25 micrograms in 25 g of the liver and kidney.

摘要

开发了在pH - 2.0条件下通过水和乙腈从尸体材料中分离曲唑酮的方法,这些方法可用于专家实践。推荐乙腈法用于日常实践,因为它能分离出约60%的曲唑酮,并获得提取物中提取物含量较低的提取物。用酸化水分离曲唑酮时,在25克肝脏中的检测限为50微克,用乙腈分离时,在25克肝脏和肾脏中的检测限为25微克。

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