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[抗炎药物及修复过程刺激剂在心肌梗死中的应用]

[The use of anti-inflammatory agents and stimulators of reparative processes in myocardial infarction].

作者信息

Iabluchanskiĭ N I, Vlasenko M A, Kopitsa N I, Dykun Ia V, Sokrut V N

出版信息

Vrach Delo. 1989 May(5):22-5.

PMID:2773422
Abstract

Agents effecting healing of the infarction zone were used in treatment of 326 patients with macrofocal myocardial infarction. In hyporeactive myocardial infarction stimulators of reparative processes, namely, methyluracil, sodium nucleinate, riboxin, retabolil, phenabolil). In hypereactive myocardial infarction antiinflammatory agents (amidopyrin, butadion, ibuprophen, indomethacin and oth.) were used beginning with the first days while stimulators of reparative processes were used beginning with the 3-4 days. Inclusion into treatment of agents optimizing healing of the myocardial infarction improved the clinical course of the disease, reduced manifestations of cardiac insufficiency and disorders of the cardiac rhythm.

摘要

采用促进梗死区愈合的药物治疗326例大片灶性心肌梗死患者。在反应性低下的心肌梗死中,使用修复过程刺激剂,即甲基尿嘧啶、核酸钠、三磷酸腺苷、苯丙酸诺龙、苯那君)。在反应性亢进的心肌梗死中,从发病第一天起使用抗炎药物(氨基比林、布他酮、布洛芬、吲哚美辛等),而修复过程刺激剂从第3 - 4天起使用。在治疗中加入优化心肌梗死愈合的药物可改善疾病的临床病程,减轻心功能不全和心律失常的表现。

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