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[风湿患者对多糖A的分泌性及全身性体液免疫反应]

[The secretory and systemic humoral immune response to polysaccharide A in patients with rheumatism].

作者信息

Briko N I, Shmidt E I, Grushchinskaia I A, Shikhman A R

出版信息

Vestn Akad Med Nauk SSSR. 1989(6):37-8.

PMID:2773560
Abstract

The level of sIgA saliva antibodies and Ig(M + G + A) serum antibodies to group polysaccharide A of streptococcus was studied in healthy donors and patients with streptococcal angina and rheumatic fever. It was shown that an elevated level of secretory and serum antibodies to polysaccharide A was registered in patients with angina and rheumatic fever reliably more frequently than in healthy donors. Independence of local and systemic humoral immune response to polysaccharide A was established.

摘要

对健康供体以及患有链球菌性心绞痛和风湿热的患者,研究了其唾液中分泌型免疫球蛋白A(sIgA)抗体以及血清中针对链球菌A群多糖的免疫球蛋白M、G、A(IgM + G + A)抗体水平。结果显示,与健康供体相比,患有心绞痛和风湿热的患者中,针对多糖A的分泌型和血清抗体水平升高的情况确实更为常见。研究还证实了针对多糖A的局部和全身体液免疫反应相互独立。

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