Duran Serdar Sadık, Kavuncuoğlu Sultan, Sarı Ferhat, Aldemir Esin Yıldız, Kavçık Nazlı, Demir Ferhat
Clinic of Pediatrics, Kanuni Sultan Süleyman Training and Research Hospital, İstanbul, Turkey.
Turk Pediatri Ars. 2016 Sep 1;51(3):128-134. doi: 10.5152/TurkPediatriArs.2016.3453. eCollection 2016 Sep.
This study aimed to investigate the perinatal mortality rate with 37 864 deliveries which occured in two different periods in a single center, to compare the components of perinatal mortality and affecting factors with the results of the study related with perinatal mortality which we conducted in 1999 and to emphasize the precautions directed to reduce mortality rates.
All live births and stillbirths which occurred in Bakırköy Obstetrics and Pediatrics Training and Research Hospital between January 2007 and December 2007 were evaluated. The results were compared with the results of the study conducted in 1999. Newborns with a weight above five hundred grams and a gestational age above 22 weeks were enrolled in the study. The stillbirth rate, early neonatal mortality rate, late neonatal mortality rate, perinatal mortality rate and corrected perinatal mortality rate were calculated. Modified Wigglesworth Classification was used for evaluating the perinatal mortality and the subjects were examined in 7 groups. The characteristics belonging to the years of 2007 and 1999 were examined, the differences were recorded and the results were discussed. When the two periods were compared, it was observed that the perinatal mortality rate increased from 23.5‰ to 26‰.
When the causes were investigated, it was observed that the stillbirth rate was increased in 2007 (84%) and especially congenital anomalies had an important role in this increment. The early neonatal mortality rate declined from 0.8% in 1999 to 0.4% in 2007. It was found that especially the premature mortality rate (Group 3) and the mortality rate related with perinatal asphyxia (Group 4) were significantly decreased.
The decrease in early neonatal mortality rate could be best explained by productive operation of the new neonatal intensive care unit which had been established after 2002.
本研究旨在调查在一个中心两个不同时期发生的37864例分娩的围产期死亡率，将围产期死亡率的构成部分及影响因素与我们1999年进行的围产期死亡率相关研究结果进行比较，并强调为降低死亡率而采取的预防措施。
对2007年1月至2007年12月在巴克尔柯伊妇产儿科学培训与研究医院发生的所有活产和死产进行评估。将结果与1999年进行的研究结果进行比较。体重超过500克、孕周超过22周的新生儿纳入研究。计算死产率、早期新生儿死亡率、晚期新生儿死亡率、围产期死亡率和校正围产期死亡率。采用改良的威格尔斯沃思分类法评估围产期死亡率，将研究对象分为7组进行检查。检查2007年和1999年的特征，记录差异并讨论结果。比较两个时期时，发现围产期死亡率从23.5‰上升至26‰。
调查原因时发现，2007年死产率上升（84%），尤其是先天性异常在这一上升中起重要作用。早期新生儿死亡率从1999年的0.8%降至2007年的0.4%。发现特别是早产死亡率（第3组）和与围产期窒息相关的死亡率（第4组）显著下降。
2002年后建立的新的新生儿重症监护病房的有效运作最能解释早期新生儿死亡率的下降。
