Nobrega Aglaer Alves da, Mendes Yluska Myrna Meneses Brandão E, Miranda Marina Jorge de, Santos Augusto César Cardoso Dos, Lobo Andréa de Paula, Porto Denise Lopes, França Giovanny Vinícius Araújo de
Secretaria de Vigilância em Saúde, Ministério da Saúde, Brasília, Brasil.
Cad Saude Publica. 2022 Jan 12;38(1):e00003121. doi: 10.1590/0102-311X00003121. eCollection 2022.
Perinatal mortality includes fetal mortality and early neonatal mortality (0 to 6 days of life). The study described perinatal deaths in Brazil in 2018 according to the modified Wigglesworth classification. The data sources were the Brazilian Mortality Information System and the Brazilian Information System on Live Births. Fetal mortality and perinatal mortality rates were calculated per 1,000 total births (live births plus stillbirths) and the early neonatal mortality rate per 1,000 live births, compared using their respective 95% confidence intervals (95%CI). Perinatal deaths were classified in groups of antepartum causes, congenital anomalies, prematurity, asphyxia, and specific causes. For each group of causes, the study calculated the number of deaths by weight group, in addition to mortality rates and respective 95%CI, besides the spatial distribution of mortality rates by state of Brazil. A total of 35,857 infant deaths were recorded, of which 18,866 (52.6%) were early neonatal deaths, while stillbirths totaled 27,009. Perinatal deaths totaled 45,875, for a mortality rate of 15.5‰ births. The highest mortality rate (7.6‰; 7.5‰-7.7‰) was observed in the antepartum group, followed by prematurity (3.6‰; 3.6‰-3.7‰). In the antepartum group, 14 of the 27 states (eight of which in the Northeast and four in the North) presented perinatal mortality rates above the national rate. Perinatal mortality in Brazil was high, and most deaths could have been prevented with investment in prenatal and childbirth care.
围产期死亡率包括胎儿死亡率和早期新生儿死亡率（出生后0至6天）。该研究根据改良的威格尔斯沃思分类法描述了2018年巴西的围产期死亡情况。数据来源为巴西死亡率信息系统和巴西活产信息系统。胎儿死亡率和围产期死亡率按每1000例总出生数（活产数加死产数）计算，早期新生儿死亡率按每1000例活产数计算，并使用各自的95%置信区间（95%CI）进行比较。围产期死亡分为产前原因、先天性异常、早产、窒息和特定原因等组。对于每组原因，该研究除计算死亡率及其各自的95%CI外，还按体重组计算死亡人数，以及巴西各州死亡率的空间分布情况。共记录了35857例婴儿死亡，其中18866例（52.6%）为早期新生儿死亡，死产总数为27009例。围产期死亡总数为45875例，死亡率为15.5‰。产前组的死亡率最高（7.6‰；7.5‰ - 7.7‰），其次是早产（3.6‰；3.6‰ - 3.7‰）。在产前组中，27个州中有14个州（其中8个在东北部，4个在北部）的围产期死亡率高于全国水平。巴西的围产期死亡率很高，通过对产前和分娩护理进行投资，大多数死亡本可避免。
