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采用多锚点法对31例1型神经纤维瘤病患者的营养不良性脊柱侧弯进行单纯后路手术矫正。

Posterior-only surgical correction of dystrophic scoliosis in 31 patients with neurofibromatosis Type 1 using the multiple anchor point method.

作者信息

Deng Ang, Zhang Hong-Qi, Tang Ming-Xing, Liu Shao-Hua, Wang Yu-Xiang, Gao Qi-Le

机构信息

Department of Spine Surgery, Xiangya Hospital of Central South University, ChangSha, China.

出版信息

J Neurosurg Pediatr. 2017 Jan;19(1):96-101. doi: 10.3171/2016.7.PEDS16125. Epub 2016 Oct 14.

Abstract

OBJECTIVE The objective of this study was to evaluate the clinical efficacy of posterior-only surgical correction of dystrophic scoliosis in patients with neurofibromatosis Type 1 (NF1) using a multiple anchor point method (MAPM). METHODS From 2005 to 2014, 31 patients (mean age 13.5 years old, range 10-22 years old) suffering from dystrophic scoliosis associated with NF1 underwent posterior-only surgical correction using a MAPM. The apex of the deformity was thoracic (n = 25), thoracolumbar (n = 4), and lumbar (n = 2). The mean preoperative coronal Cobb angle was 69.1° (range 48.9°-91.4°). The mean Cobb angle on the side-bending radiograph of the convex side was 58.2° (range 40°-79.8°). The mean flexibility and apical vertebral rotation (AVR) were 15.6% (range 8.3%-28.2%) and 2.5° (range 2°-3°), respectively. The mean angle of sagittal kyphosis was 58.3° (range 34.1°-79.6°). RESULTS The mean follow-up period was 53 months (range 12-96 months). The mean postoperative coronal Cobb angle was 27.4° (range 16.3°-46.7°). Postoperatively, the mean AVR and angle of sagittal kyphosis were 1.2° (range 1°-2°) and 22.4° (range 4.2°-36.3°), respectively. All patients showed good correction of all indices postoperatively. The mean postoperative correction rate was 58.7% (range 46.3%-74.1%). At the final follow-up evaluation, the corrective loss rate of the Cobb angle was only 2.3%. Only 1 patient required revision surgery. No severe complications such as spinal cord, neural, or large vascular injury occurred during the operation. CONCLUSIONS Posterior-only surgical correction of dystrophic scoliosis in patients with NF1 using a MAPM could yield satisfactory clinical efficacy of correction and fusion.

摘要

目的 本研究的目的是评估采用多锚点方法(MAPM)对1型神经纤维瘤病(NF1)患者的营养不良性脊柱侧弯进行单纯后路手术矫正的临床疗效。方法 2005年至2014年,31例患有与NF1相关的营养不良性脊柱侧弯的患者(平均年龄13.5岁,范围10 - 22岁)采用MAPM进行了单纯后路手术矫正。畸形顶点位于胸椎(n = 25)、胸腰段(n = 4)和腰椎(n = 2)。术前冠状面Cobb角平均为69.1°(范围48.9° - 91.4°)。凸侧侧弯位X线片上的Cobb角平均为58.2°(范围40° - 79.8°)。平均柔韧性和顶椎旋转(AVR)分别为15.6%(范围8.3% - 28.2%)和2.5°(范围2° - 3°)。矢状面后凸角平均为58.3°(范围34.1° - 79.6°)。结果 平均随访期为53个月(范围12 - 96个月)。术后冠状面Cobb角平均为27.4°(范围16.3° - 46.7°)。术后,平均AVR和矢状面后凸角分别为1.2°(范围1° - 2°)和22.4°(范围4.2° - 36.3°)。所有患者术后各项指标均显示良好的矫正效果。术后平均矫正率为58.7%(范围46.3% - 74.1%)。在末次随访评估时,Cobb角的矫正丢失率仅为2.3%。仅1例患者需要翻修手术。手术过程中未发生脊髓、神经或大血管损伤等严重并发症。结论 采用MAPM对NF1患者的营养不良性脊柱侧弯进行单纯后路手术矫正可产生令人满意的矫正和融合临床疗效。

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