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机器人辅助与腹腔镜左外叶切除术:倾向评分匹配队列研究对手术结果和成本的分析

Robotic-Assisted Versus Laparoscopic Left Lateral Sectionectomy: Analysis of Surgical Outcomes and Costs by a Propensity Score Matched Cohort Study.

作者信息

Salloum Chady, Lim Chetana, Lahat Eylon, Gavara Concepcion Gomez I, Levesque Eric, Compagnon Philippe, Azoulay Daniel

机构信息

Department of Hepato-Biliary and Pancreatic Surgery and Liver Transplantation, AP-HP Henri Mondor Hospital, 51 Avenue De Lattre De Tassigny, 94010, Créteil, France.

Department of Anesthesia and Liver Intensive Care Unit, AP-HP Henri Mondor Hospital, Créteil, France.

出版信息

World J Surg. 2017 Feb;41(2):516-524. doi: 10.1007/s00268-016-3736-2.

Abstract

BACKGROUND

After comparing with open approach, left lateral sectionectomy (LLS) has become standard in terms of short-term outcomes without jeopardizing long-term survival when performed for malignancy. The aim of this study was to compare the short-term and economic outcomes of laparoscopic (L-LLS) and robotic (R-LLS) LLS.

METHODS

All consecutive patients who underwent L-LLS or R-LLS from 1997 to 2014 were analyzed. Short-term and economic outcomes were compared between the two groups using a propensity score matching (PSM).

RESULTS

Ninety-six consecutive cases of LLS were performed using the laparoscopic (80 cases; 83 %) or robotic (16 cases; 17 %) approach. The two groups were similar for operative and surgical outcomes. Operation time was similar in the R-LLS compared to the L-LLS group (190 vs. 162 min; p = 0.10). Perioperative costs were higher (1457 € vs. 576 €; p < 0.0001) in the R-LLS group than in the L-LLS group; however, postoperative costs were similar between the two groups (4065 € in the R-LLS group vs. 5459 € in the L-LLS group; p = 0.30). Total costs were similar between the two groups (5522 € in the R-LLS group vs. 6035€ in the L-LLS group; p = 0.70). The PSM included 14 patients for each group. Surgical and economic outcomes remained similar after PSM, except for total operating time which was significantly longer in the R-LLS group than in the L-LLS group.

CONCLUSIONS

Even if feasible and safe, the robotic approach does not seem so far to offer additional benefit in terms of intra- and postoperative outcomes over the laparoscopic approach in patients requiring LLS. Total costs associated with the R-LLS group are not greater than that associated with the L-LLS group, which is the standard of care so far.

摘要

背景

与开放手术相比,左侧肝段切除术(LLS)在治疗恶性肿瘤时,就短期疗效而言已成为标准术式,且不影响长期生存率。本研究旨在比较腹腔镜下左侧肝段切除术(L-LLS)和机器人辅助左侧肝段切除术(R-LLS)的短期疗效和经济成本。

方法

分析1997年至2014年间所有连续接受L-LLS或R-LLS手术的患者。采用倾向评分匹配法(PSM)比较两组的短期疗效和经济成本。

结果

连续96例LLS手术采用腹腔镜手术(80例;83%)或机器人辅助手术(16例;17%)。两组的手术和外科疗效相似。R-LLS组的手术时间与L-LLS组相似(190分钟对162分钟;p = 0.10)。R-LLS组的围手术期成本高于L-LLS组(1457欧元对576欧元;p < 0.0001);然而,两组的术后成本相似(R-LLS组为4065欧元,L-LLS组为5459欧元;p = 0.30)。两组的总成本相似(R-LLS组为5522欧元,L-LLS组为6035欧元;p = 0.70)。PSM每组纳入14例患者。PSM后手术和经济成本仍相似,但R-LLS组的总手术时间显著长于L-LLS组。

结论

即使机器人辅助手术可行且安全,但就LLS患者的术中和术后疗效而言,与腹腔镜手术相比,目前似乎并未带来额外益处。R-LLS组的总成本不高于L-LLS组,而L-LLS组是目前的标准治疗方式。

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