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Metronidazole-induced neurotoxicity presenting with sudden bilateral hearing loss, encephalopathy, and cerebellar dysfunction.

作者信息

Agah Elmira, Habibi Arman, Naderi Hamed, Tafakhori Abbas

机构信息

School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

NeuroImmunology Research Association (NIRA), Universal Scientific Education and Research Network (USERN), Tehran, Iran.

出版信息

Eur J Clin Pharmacol. 2017 Feb;73(2):249-250. doi: 10.1007/s00228-016-2147-5. Epub 2016 Oct 15.

DOI:10.1007/s00228-016-2147-5
PMID:27744577
Abstract
摘要

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本文引用的文献

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Sudden sensorineural hearing loss secondary to metronidazole ototoxicity.甲硝唑耳毒性继发的突发性感音神经性听力损失
Med J Aust. 2015 Sep 21;203(6):253-253e.1. doi: 10.5694/mja15.00222.
2
Metronidazole-induced encephalopathy with contrast enhancing lesions on MRI.甲硝唑诱发的脑病，磁共振成像（MRI）显示有强化病灶
J Neurol Sci. 2015 May 15;352(1-2):129-31. doi: 10.1016/j.jns.2015.03.039. Epub 2015 Mar 31.
3
Sudden hearing loss subsequent to diarrhea: what is the missing link?腹泻后继发突发性聋：缺失的环节是什么？
一名年轻患者的甲硝唑诱发急性小脑炎：不寻常的起病、延迟缓解及特征性影像学表现
Cureus. 2024 Mar 13;16(3):e56098. doi: 10.7759/cureus.56098. eCollection 2024 Mar.
4
Metronidazole, an Uncommon Cause of Dizziness and Ataxia in the Emergency Department: A Case Report.甲硝唑：急诊科头晕和共济失调的罕见病因：一例报告
Clin Pract Cases Emerg Med. 2021 May;5(2):239-241. doi: 10.5811/cpcem.2021.3.52046.
5
A Pilot Evaluation of the Possible Association of Metronidazole With Neurodevelopmental Outcomes in Premature Neonates.甲硝唑与早产儿神经发育结局可能关联的初步评估。
J Pediatr Pharmacol Ther. 2021;26(5):455-459. doi: 10.5863/1551-6776-26.5.455. Epub 2021 Jun 28.
6
Serum Bilirubin Level as a Potential Marker for the Hearing Outcome in Severe-Profound Bilateral Sudden Deafness.血清胆红素水平作为重度-极重度双侧突发性聋听力转归的潜在标志物。
Otol Neurotol. 2019 Jul;40(6):728-735. doi: 10.1097/MAO.0000000000002287.
7
A case of methylprednisolone treatment for metronidazole-induced encephalopathy.1例甲基强的松龙治疗甲硝唑诱发脑病的病例。
BMC Neurol. 2019 Mar 30;19(1):49. doi: 10.1186/s12883-019-1278-6.
8
Metronidazole-induced encephalopathy: a systematic review.甲硝唑诱导的脑病：系统评价。
J Neurol. 2020 Jan;267(1):1-13. doi: 10.1007/s00415-018-9147-6. Epub 2018 Dec 7.
Daru. 2014 Jan 8;22(1):15. doi: 10.1186/2008-2231-22-15.
4
A rare adverse effect of metronidazole: nervous system symptoms.
Pediatr Emerg Care. 2013 Jun;29(6):751-2. doi: 10.1097/PEC.0b013e318294f389.
5
Metronidazole-induced central nervous system toxicity: a systematic review.甲硝唑诱发的中枢神经系统毒性：一项系统评价
Clin Neuropharmacol. 2011 Nov-Dec;34(6):241-7. doi: 10.1097/WNF.0b013e3182334b35.
6
Neurotoxic effects associated with antibiotic use: management considerations.与抗生素使用相关的神经毒性作用：管理注意事项。
Br J Clin Pharmacol. 2011 Sep;72(3):381-93. doi: 10.1111/j.1365-2125.2011.03991.x.
7
Physician's guide to pharmacovigilance: terminology and causality assessment.《医师药物警戒指南：术语与因果关系评估》
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Metronidazole ototoxicity--report of two cases.甲硝唑耳毒性——两例报告。
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