Gastroenterology, Liver Center, Beth Israel Deaconess Medical Center, Harvard University, 110 Francis St, Boston, MA 02115, USA.
Gastroenterology, Liver Center, Beth Israel Deaconess Medical Center, Harvard University, 110 Francis St, Boston, MA 02115, USA.
Med Clin North Am. 2016 Nov;100(6):1303-1327. doi: 10.1016/j.mcna.2016.06.010. Epub 2016 Sep 13.
The progressively increasing rates of obesity have led to a worldwide epidemic of nonalcoholic fatty liver disease (NAFLD), the hepatic manifestation of the metabolic syndrome. It is currently the most common cause of liver disease worldwide and projected to be the leading indication for liver transplantation in the United States by 2020. NAFLD is associated with both liver-related and overall mortality. Undoubtedly, nutrition interventions are key in the treatment of NAFLD, to reverse the disease, and prevent disease progression, complications, and associated comorbidities, including cardiovascular disease and diabetes.
不断增加的肥胖率导致了非酒精性脂肪性肝病(NAFLD)的全球流行,这是代谢综合征在肝脏的表现。NAFLD 目前是全世界最常见的肝脏疾病病因,预计到 2020 年将成为美国肝移植的首要适应证。NAFLD 与肝脏相关和总体死亡率相关。毫无疑问,营养干预是治疗 NAFLD 的关键,可逆转疾病并预防疾病进展、并发症和相关合并症,包括心血管疾病和糖尿病。