Agarwala Manoj Kumar, Asad Azeez, Gummadi Naveen, Chidambaram Sundar, Venkateswaralu J
Apollo Hospitals, Hyderabad, India.
Apollo Hospitals, Hyderabad, India.
Indian Heart J. 2016 Sep;68 Suppl 2(Suppl 2):S69-S71. doi: 10.1016/j.ihj.2016.05.002. Epub 2016 May 20.
Carotid artery dissection (CAD) is a frequent cause of stroke, accounting for up to 25% of all ischemic strokes in young and middle-aged patients. It may be traumatic or spontaneous, with multi-factorial etiology. A tear in the arterial wall causes intrusion of blood within its layers, producing intra-luminal stenosis, or aneurysmal dilatation. Thrombo-embolism arising from this anatomic disruption has been postulated as the essential stroke mechanism in CAD. Bilateral internal carotid artery dissection (ICAD) has been rarely reported. Antiplatelets and anticoagulation remain standard therapy for CAD. However, in patients with either expanding pseudoaneurysms, severe flow compromise, worsening symptoms despite anticoagulation or contraindication to anticoagulation, endovascular stenting is beneficial. We describe a patient with ischemic stroke from spontaneous bilateral ICAD with completely occluded left ICA. Having failed medical therapy with antiplatelets and anticoagulants due to extensive loss of carotid vascular supply, he was managed successfully with endovascular stenting with good neurological recovery.
颈动脉夹层(CAD)是中风的常见病因,在中青年患者的所有缺血性中风中占比高达25%。它可能是外伤性的或自发性的,病因是多因素的。动脉壁撕裂会导致血液侵入其各层,产生管腔内狭窄或动脉瘤样扩张。这种解剖结构破坏引起的血栓栓塞被认为是CAD中中风的主要机制。双侧颈内动脉夹层(ICAD)鲜有报道。抗血小板和抗凝治疗仍是CAD的标准疗法。然而,对于有扩张性假性动脉瘤、严重血流受限、抗凝治疗后症状仍恶化或有抗凝禁忌证的患者,血管内支架置入术是有益的。我们描述了一名因自发性双侧ICAD导致缺血性中风且左侧颈内动脉完全闭塞的患者。由于颈动脉血管供应大量丧失,抗血小板和抗凝药物治疗失败,他通过血管内支架置入术成功治疗,神经功能恢复良好。