Department of Vascular Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
Department of Vascular Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
J Thorac Cardiovasc Surg. 2017 Jan;153(1):57-65. doi: 10.1016/j.jtcvs.2016.09.022. Epub 2016 Sep 22.
How to choose the proximal landing zone in endovascular interventions for a patient with a patent retrograde false lumen in dissection of the ascending aorta and aortic arch remains unclear. This study sought to report the safety and efficiency of inducing thrombosis of the retrograde false lumen to enhance a proximal landing zone to treat retrograde type A aortic dissection.
This study included 9 patients with retrograde type A aortic dissection treated with a 2-stage operation strategy between January 2015 and January 2016. Coil and Onyx glue embolization was performed to create a thrombogenic environment in the retrograde false lumen of the ascending aorta and aortic arch as the first-stage operation, followed by thoracic endovascular aortic repair (TEVAR) with the chimney technique as the second-stage operation.
Complete thrombosis in a retrograde false lumen of the ascending aorta and aortic arch was found in all 9 patients before the second-stage operation was performed. The rate of successful TEVAR was 100%, with the single-chimney technique performed in 6 patients to reconstruct the left subclavian artery and the double-chimney technique performed in 3 patients to reconstruct the left common carotid artery. No morbidities, no stent graft-induced new dissection, or deaths occurred in the hospital and during the 12-month follow-up period. Positive morphological remodeling was evidenced in all cases.
The short-term outcomes of the patients in this study were satisfactory. Inducing thrombosis of the retrograde false lumen to enhance the proximal landing zone for TEVAR may be a safe and effective approach to treating retrograde type A aortic dissection.
在升主动脉和主动脉弓夹层中,如何选择血管内介入治疗的近端着陆区,对于逆行假腔通畅的患者而言仍不明确。本研究旨在报告通过诱导逆行假腔血栓形成以增强近端着陆区,从而治疗逆行型 A 型主动脉夹层的安全性和有效性。
本研究纳入了 2015 年 1 月至 2016 年 1 月期间采用两阶段手术策略治疗的 9 例逆行型 A 型主动脉夹层患者。作为第一阶段手术,在升主动脉和主动脉弓的逆行假腔中进行线圈和 Onyx 胶栓塞,以创建血栓形成环境,然后进行胸主动脉腔内修复术(TEVAR),采用烟囱技术作为第二阶段手术。
在进行第二阶段手术之前,所有 9 例患者的升主动脉和主动脉弓逆行假腔均完全血栓形成。100%的患者成功实施了 TEVAR,其中 6 例患者采用单烟囱技术重建左锁骨下动脉,3 例患者采用双烟囱技术重建左颈总动脉。患者在院期间和 12 个月随访期间均无并发症、支架移植物导致的新发夹层或死亡。所有病例均显示出阳性的形态学重塑。
本研究中患者的短期结果令人满意。通过诱导逆行假腔血栓形成来增强 TEVAR 的近端着陆区可能是一种安全有效的治疗逆行型 A 型主动脉夹层的方法。