Geoghegan K F, Dixon H B
Department of Biochemistry, University of Cambridge, U.K.
Biochem J. 1989 May 15;260(1):295-6. doi: 10.1042/bj2600295.
2-Aminoethylarsonic acid was prepared from 2-choloethylarsonic acid. The route constitutes a new procedure for making primary amines from haloalkanes; chloride was displaced by treatment with 2-aminoethanol at 70 degrees C, and the product was converted into the required primary amine by treatment with periodate.
2-氨基乙胂酸由2-氯乙胂酸制备而成。该路线构成了一种从卤代烷制备伯胺的新方法;通过在70℃下用2-氨基乙醇处理来取代氯,然后用高碘酸盐处理将产物转化为所需的伯胺。