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一项关于15至45岁接受慢性血液透析女性性功能障碍主要决定因素的研究。

A study of the main determinants of sexual dysfunction in women aged 15-45 years on chronic hemodialysis.

作者信息

Hekmat Reza, Maghsudloo Faeze, Mohebi Mahmood, Rezaee Sayed Abdolrahim, Vakili Rosita, Panah Hoshang Rafat

机构信息

Department of Nephrology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.

Inflammation and Inflammatory Diseases Division, Immunology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

Saudi J Kidney Dis Transpl. 2016 Sep-Oct;27(5):916-920. doi: 10.4103/1319-2442.190816.

Abstract

Sexual dysfunction (SD) is a common problem in patients with the end-stage renal disease. In contrast to SD in males, relatively little work has been performed in the field of SD in females. In this study, we tried to identify the main determinants of SD in women aged 15-45year-old on chronic hemodialysis (HD). One hundred-forty female patients aged 15-45-year-old on chronic HD were studied in the winter of the year 2013. Healthy relatives of the patients were chosen as controls and matched for age, level of education, marital status, and income. Both cases and controls were interviewed by the same female interviewer. The Arizona Sexual Experiences Scale (ASEX) was used as a questionnaire. A significant correlation was found between the total ASEX score and age and duration on HD (r = 0.599, P = 0.003 and r = 0.434, P = 0.043, respectively). No correlation was found between serum hemoglobin, parathormone, creatinine, iron, calcium, phosphorus, and urea reduction ratio and the ASEX score. Moreover, the correlation between the ASEX score and socioeconomic parameters like level of education and monthly income was not significant (all P >0.1). There was a significant difference in the total ASEX score between cases and controls (16.31 ± 2.50 vs. 9.80 ± 4.21, P <0.001). Our study suggests that sexual function in chronic hemodialyzed female patients is mainly impacted by age and duration on HD.

摘要

性功能障碍(SD)是终末期肾病患者的常见问题。与男性性功能障碍相比,女性性功能障碍领域的研究相对较少。在本研究中,我们试图确定15 - 45岁接受慢性血液透析(HD)的女性性功能障碍的主要决定因素。2013年冬季,对140名年龄在15 - 45岁的接受慢性血液透析的女性患者进行了研究。选择患者的健康亲属作为对照,并在年龄、教育程度、婚姻状况和收入方面进行匹配。病例组和对照组均由同一名女性访谈员进行访谈。使用亚利桑那性体验量表(ASEX)作为调查问卷。发现ASEX总分与年龄和血液透析时长之间存在显著相关性(r = 0.599,P = 0.003;r = 0.434,P = 0.043)。未发现血清血红蛋白、甲状旁腺激素肌酐、铁、钙、磷和尿素清除率与ASEX评分之间存在相关性。此外,ASEX评分与教育程度和月收入等社会经济参数之间的相关性不显著(所有P>0.1)。病例组和对照组的ASEX总分存在显著差异(分别为16.31±2.50和9.80±4.21,P<0.001)。我们的研究表明,慢性血液透析女性患者的性功能主要受年龄和血液透析时长的影响。

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