Zhou Yujia, Wang Gesheng, Liu Jialin, Du Yong, Wang Lei, Wang Xiaoyong
Department of Neurosurgery, Dongfang Hospital of Beijing University of Chinese Medicine, Beijing, China (mainland).
Med Sci Monit. 2016 Oct 14;22:3689-3693. doi: 10.12659/MSM.896982.
BACKGROUND The aim of this study was to evaluate the application of medical adhesive glue for tension-reduced duraplasty in decompressive craniotomy. MATERIAL AND METHODS A total of 56 cases were enrolled for this study from Jan 2013 to May 2015. All patients underwent decompressive craniotomy and the dura was repaired in all of them with tension-reduced duraplasty using the COMPONT medical adhesive to glue artificial dura together. The postoperative complications and the healing of dura mater were observed and recorded. RESULTS No wound infection, epidural or subdural hematoma, cerebrospinal fluid leakage, or other complications associated with the procedure occurred, and there were no allergic reactions to the COMPONT medical adhesive glue. The second-phase surgery of cranioplasty was performed at 3 to 6 months after the decompressive craniotomy in 32 out of the 56 cases. During the cranioplasty we observed no adherence of the artificial dura mater patch to the skin flap, no residual COMPONT glue, or hydropic or contracture change of tissue at the surgical sites. Additionally, no defect or weakening of the adherence between the artificial dura mater patch and the self dura matter occurred. CONCLUSIONS COMPONT medical adhesive glue is a safe and reliable tool for tension-reduced duraplasty in decompressive craniotomy.
背景 本研究旨在评估医用胶水在减压开颅术中用于减张硬脑膜成形术的应用效果。材料与方法 2013年1月至2015年5月共纳入56例患者进行本研究。所有患者均接受减压开颅术，并且全部使用COMPONT医用胶水将人工硬脑膜粘合在一起进行减张硬脑膜成形术修复硬脑膜。观察并记录术后并发症及硬脑膜愈合情况。结果 未发生伤口感染、硬膜外或硬膜下血肿、脑脊液漏或与该手术相关的其他并发症，且未出现对COMPONT医用胶水的过敏反应。56例患者中有32例在减压开颅术后3至6个月进行了颅骨成形二期手术。在颅骨成形术中，我们观察到人工硬脑膜补片与皮瓣无粘连，无COMPONT胶水残留，手术部位组织无水肿或挛缩改变。此外，人工硬脑膜补片与自体硬脑膜之间的粘连无缺损或减弱。结论 COMPONT医用胶水是减压开颅术中用于减张硬脑膜成形术的一种安全可靠的工具。
