Stabilization of actin filaments by ATP and inorganic phosphate.
作者信息
Dancker P, Fischer S
机构信息
Institut für Zoologie der Technischen Hochschule Darmstadt, Bundesrepublik Deutschland.
出版信息
Z Naturforsch C J Biosci. 1989 Jul-Aug;44(7-8):698-704. doi: 10.1515/znc-1989-7-824.
PMID:2775410
Abstract
Both inorganic orthophosphate and ATP stabilize actin filaments. This is reflected by a reduced nucleotide exchange and by a protection against filament breakdown by SDS or KI. When the filament-stabilizing effect of ATP was maximal, only about 15% of the actin subunits of the filament had bound one molecule of the nucleotide offered in the stabilizing solution.
摘要
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