Chandler J D, Patten J
Department of Psychiatry, College of Medicine, University of Iowa, Iowa City.
J Geriatr Psychiatry Neurol. 1989 Apr-Jun;2(2):101-5. doi: 10.1177/089198878900200210.
Computed tomography of the head (HCT) was studied prospectively in 42 new geriatric psychiatry patients. Scans were obtained in 88% of the sample. Subjects underwent a complete evaluation by a geriatric psychiatrist who was blind to the HCT results. The HCT was abnormal in 32 (86%) of the 37 patients who had a scan. The most frequent finding was atrophic changes, which were discovered in ten (27%) of the 37 patients. Subcortical vascular disease was found in 14 patients (38%). Mixed pictures with both vascular disease and atrophic changes were found in nine (24%). The only statistically significant predictor of an abnormal HCT was an abnormal neurobehavioral examination. While the information gained from the HCT did not add appreciably to the clinical evaluation in determining whether there was an organic or idiopathic psychiatric syndrome, it was crucial in determining the location and nature of the central nervous system lesions.
对42名老年精神病学新患者进行了头部计算机断层扫描(HCT)的前瞻性研究。88%的样本进行了扫描。受试者接受了一位对HCT结果不知情的老年精神病医生的全面评估。在进行扫描的37名患者中,32名(86%)的HCT结果异常。最常见的发现是萎缩性改变,在37名患者中有10名(27%)发现了这种改变。14名患者(38%)发现了皮质下血管疾病。9名患者(24%)发现了血管疾病和萎缩性改变并存的混合情况。HCT异常的唯一具有统计学意义的预测因素是神经行为检查异常。虽然从HCT获得的信息在确定是器质性还是特发性精神综合征方面对临床评估没有明显增加,但在确定中枢神经系统病变的位置和性质方面至关重要。