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足月单胎妊娠新生儿死亡的潜在原因:美国在家分娩与医院分娩情况对比

Underlying causes of neonatal deaths in term singleton pregnancies: home births versus hospital births in the United States.

作者信息

Grünebaum Amos, McCullough Laurence B, Arabin Birgit, Dudenhausen Joachim, Orosz Brooke, Chervenak Frank A

机构信息

Department of Obstetrics and Gynecology, Weill Medical College of Cornell University, New York, NY.

Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX.

出版信息

J Perinat Med. 2017 Apr 1;45(3):349-357. doi: 10.1515/jpm-2016-0200.

Abstract

INTRODUCTION

The objective of this study was to evaluate the underlying causes of neonatal mortality (NNM) in midwife-attended home births and compare them to hospital births attended by a midwife or a physician in the United States (US).

METHODS

A retrospective cohort study of the Centers for Disease Control (CDC) linked birth/infant death data set (linked files) for 2008 through 2012 of singleton, term (≥37 weeks) births and normal newborn weights (≥2500 grams).

RESULTS

Midwife-attended home births had the highest rate of neonatal deaths [122/95,657 neonatal mortality (NNM) 12.75/10,000; relative risk (RR): 3.6, 95% confidence interval (CI) 3-4.4], followed by hospital physician births (8695/14,447,355 NNM 6.02/10,000; RR: 1.7 95% CI 1.6-1.9) and hospital midwife births (480/1,363,199 NNM 3.52/10,000 RR: 1). Among midwife-assisted home births, underlying causes attributed to labor and delivery caused 39.3% (48/122) of neonatal deaths (RR: 13.4; 95% CI 9-19.9) followed by 29.5% due to congenital anomalies (RR: 2.5; 95% CI 1.8-3.6), and 12.3% due to infections (RR: 4.5; 95% CI 2.5-8.1).

COMMENT

There are significantly increased risks of neonatal deaths among midwife-attended home births associated with three underlying causes: labor and delivery issues, infections, and fetal malformations. This analysis of the causes of neonatal death in planned home birth shows that it is consistently riskier for newborns to deliver at home than at the hospital. Physicians, midwives, and other health care providers have a professional responsibility to share information about the clinical benefits and risks of clinical management.

摘要

引言

本研究的目的是评估由助产士接生的家庭分娩中新生儿死亡(NNM)的潜在原因,并将其与美国由助产士或医生接生的医院分娩进行比较。

方法

对疾病控制中心(CDC)2008年至2012年单胎、足月(≥37周)出生且新生儿体重正常(≥2500克)的出生/婴儿死亡关联数据集(关联文件)进行回顾性队列研究。

结果

由助产士接生的家庭分娩新生儿死亡率最高[122/95,657,新生儿死亡率(NNM)为12.75/10,000;相对风险(RR):3.6,95%置信区间(CI)3 - 4.4],其次是医院医生接生的分娩(8695/14,447,355,NNM为6.02/10,000;RR:1.7,95%CI 1.6 - 1.9)和医院助产士接生的分娩(480/1,363,199,NNM为3.52/10,000,RR:1)。在助产士协助的家庭分娩中,因分娩过程导致的潜在原因占新生儿死亡的39.3%(48/122)(RR:13.4;95%CI 9 - 19.9),其次是29.5%由于先天性异常(RR:2.5;95%CI 1.8 - 3.6),以及12.3%由于感染(RR:4.5;95%CI 2.5 - 8.1)。

评论

在由助产士接生的家庭分娩中,与三个潜在原因相关的新生儿死亡风险显著增加:分娩问题、感染和胎儿畸形。对计划在家分娩中新生儿死亡原因的分析表明,新生儿在家分娩始终比在医院分娩风险更高。医生、助产士和其他医疗保健提供者有专业责任分享有关临床管理的临床益处和风险的信息。

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