Ohno-Matsui Kyoko
Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.
Retina. 2017 Jun;37(6):1043-1048. doi: 10.1097/IAE.0000000000001348.
Despite being a major cause of visual impairment worldwide, pathologic myopia has not been clearly and consistently defined. This lack of a standardized definition has made comparisons among epidemiological studies difficult. Therefore, the purpose of this review was to summarize the definitions of pathologic myopia.
A literature search was conducted of Pubmed to identify reports presenting definitions of pathologic myopia.
Although cut-off values for refractive error and increased axial length have been used in some studies, a definition based solely on such values is considered to just show a 'high degree of myopia'. Similarly, the presence of myopic fundus lesions in addition to a high degree of myopia has been used to define pathologic myopia; however, such lesions often develop with age and they are not characteristic of pathologic myopia.
So, what is pathologic myopia? This review covers the various proposed definitions for pathologic myopia, and describes its major features such as posterior staphyloma, variation in axial length, and the presence of myopic maculopathy. Some unanswered questions that serve as signposts to areas of interest for future research have also been discussed.
尽管病理性近视是全球视力损害的主要原因之一,但其定义尚未得到清晰且一致的界定。这种缺乏标准化定义的情况使得流行病学研究之间的比较变得困难。因此,本综述的目的是总结病理性近视的定义。
在PubMed上进行文献检索,以识别呈现病理性近视定义的报告。
尽管一些研究使用了屈光不正和眼轴长度增加的临界值,但仅基于这些值的定义被认为仅显示“高度近视”。同样,除高度近视外还存在近视性眼底病变也被用于定义病理性近视;然而,此类病变常随年龄发展,并非病理性近视所特有。
那么,什么是病理性近视呢?本综述涵盖了病理性近视的各种提议定义,并描述了其主要特征,如后巩膜葡萄肿、眼轴长度变化以及近视性黄斑病变的存在。还讨论了一些未解决的问题,这些问题可作为未来研究感兴趣领域的路标。