Taleb Mona, Choi Lydia, Kim Steve
Department of Surgery at the Wayne State University School of Medicine, Detroit, MI, USA.
Karmanos Cancer Center, 4100 John R, Mail Code HW04HO, Detroit, MI, 48201, USA.
World J Surg Oncol. 2016 Oct 19;14(1):269. doi: 10.1186/s12957-016-1019-x.
After wide local excision of cutaneous melanoma, large defects not amenable to simple primary closure are often covered with skin grafts. We report our experience using the rhomboid and keystone flaps to immediately close large axial and extremity wounds after potentially curative surgery for non-head and neck melanomas.
Between January 2011 and September 2016, demographic, operative, pathologic, and outcome data were prospectively collected on 60 patients who underwent wide local excision of melanoma followed by immediate flap reconstruction. Flaps were of either rhomboid or keystone type. Chi-square analysis was used to compare relationships between factors.
All procedures were done by the senior author and as outpatient surgery. No patient required a surgical drain unless they were undergoing concomitant radical regional node dissection. Flap separation (arbitrarily defined as a >5-mm dehiscence of the suture line) occurred in 16/61 patients (26 %). No patient had flap loss. The risk of flap morbidity was significantly higher if the primary tumor was on the distal extremity-10 of 24 patients (42 %), all with keystone flaps-than if it was on the trunk or the proximal extremity (6/37 patients, 16 %), p = 0.04. There were no margins positive for either invasive or in situ melanoma in the entire cohort.
Simple transposition flaps can successfully cover large defects after melanoma excision without the need for skin grafting. Keystone flaps in the distal extremity are more prone to separation, but this is minor and does not result in flap loss. There is minimal risk of a positive margin requiring flap takedown and a second re-excision.
皮肤黑色素瘤广泛局部切除术后,无法通过简单一期缝合处理的大创面通常采用皮肤移植覆盖。我们报告了在非头颈部黑色素瘤根治性手术后,使用菱形皮瓣和梯形皮瓣立即闭合大的躯干及肢体创面的经验。
2011年1月至2016年9月,前瞻性收集了60例行黑色素瘤广泛局部切除并立即行皮瓣重建患者的人口统计学、手术、病理及预后数据。皮瓣为菱形或梯形。采用卡方分析比较各因素之间的关系。
所有手术均由资深作者完成,且为门诊手术。除非同时行根治性区域淋巴结清扫,否则无需放置手术引流管。61例患者中有16例(26%)发生皮瓣分离(定义为缝线裂开>5 mm)。无患者皮瓣坏死。如果原发肿瘤位于肢体远端,皮瓣并发症风险显著更高——24例患者中有10例(42%),均为梯形皮瓣——高于位于躯干或肢体近端的患者(37例患者中有6例,16%),p = 0.04。整个队列中,侵袭性或原位黑色素瘤均无切缘阳性情况。
简单的转移皮瓣可成功覆盖黑色素瘤切除术后的大创面,无需植皮。肢体远端的梯形皮瓣更易分离,但程度较轻,不会导致皮瓣坏死。切缘阳性需要切除皮瓣并再次切除的风险极小。