Choudhury Dwijen Kumar, Bezbaruah Babul Kumar
Department of Pharmacology, Gauhati Medical College and Hospital, Guwahati, Assam, India.
Indian J Pharmacol. 2016 Jul-Aug;48(4):377-381. doi: 10.4103/0253-7613.186207.
The aim of this study is to evaluate the prescribing pattern of analgesics and analyze the rational use of analgesic in orthopedic in-patient department of tertiary care teaching hospital, Guwahati, Assam.
An observational and cross-sectional study was carried out for 1 month from April to May 2014. Collected data included age, sex, diagnosis and line of management during the study. The generic name and the average cost of treatment per patient were evaluated using Indian Drug Review, 2014. The prescribed drugs were assessed with respective National Model List of Essential Medicines (NLEM), 2011 and the rationality of prescriptions was determined using the World Health Organization indicators of drug utilization. The patients' details were recorded in a predeigned data collection form and results were analyzed by descriptive statistics.
Out of 200 patients, 123 were male and 77 were female. The average number of analgesic per prescription was 1.46. In this study, 55.5% of patients had received single analgesic. Diclofenac was the most commonly prescribed analgesic (43.49%). During hospitalization, majority of the patients have received parenteral preparation. Gastroprotective agents and antimicrobials were frequently prescribed along with analgesics. Out of 292 analgesics prescribed, 183 (62.67%) were from the NLEM, India. Furthermore, 176 (57.19%) analgesics were prescribed by generic name. The average cost of treatment per patient was 2151.72 INR. Utilization of analgesic in terms of defined daily dose/100 bed-days was 104.01.
The percentages of analgesics prescribing from NLEM and the use of analgesic by generic name were found satisfactory. Regular educational interventions to improve prescribing practices among physicians at different levels may further promote rational prescribing.
本研究旨在评估阿萨姆邦古瓦哈蒂三级护理教学医院骨科住院部镇痛药的处方模式,并分析镇痛药的合理使用情况。
于2014年4月至5月进行了为期1个月的观察性横断面研究。收集的数据包括研究期间的年龄、性别、诊断和治疗方案。使用《2014年印度药物评论》评估每位患者的通用名和平均治疗费用。根据2011年国家基本药物示范目录(NLEM)对所开药物进行评估,并使用世界卫生组织药物利用指标确定处方的合理性。患者详细信息记录在预先设计的数据收集表中,并通过描述性统计进行分析。
200名患者中,男性123名,女性77名。每张处方的平均镇痛药数量为1.46。在本研究中,55.5%的患者接受了单一镇痛药治疗。双氯芬酸是最常开具的镇痛药(43.49%)。住院期间,大多数患者接受了胃肠保护剂和抗菌药物。在292种开具的镇痛药中,183种(62.67%)来自印度NLEM。此外,176种(57.19%)镇痛药以通用名开具。每位患者的平均治疗费用为2151.72印度卢比。按限定日剂量/100床日计算的镇痛药利用率为104.01。
发现来自NLEM的镇痛药处方百分比和通用名镇痛药的使用情况令人满意。定期开展教育干预以改善不同级别医生的处方行为,可能会进一步促进合理处方。