尼日利亚西南部门诊老年患者镇痛药物使用处方模式评估。
Evaluation of prescription pattern of analgesic use among ambulatory elderly in South-Western Nigeria.
作者信息
Akande-Sholabi Wuraola, Agha Princess C, Olowookere Olufemi O, Adebusoye Lawrence A
机构信息
Department of Clinical Pharmacy and Pharmacy Administration, Faculty of Pharmacy, University of Ibadan, Ibadan, Nigeria.
Chief Tony Anenih Geriatric Centre, University College Hospital, Ibadan, Nigeria.
出版信息
Ann Afr Med. 2020 Apr-Jun;19(2):131-136. doi: 10.4103/aam.aam_57_19.
BACKGROUND
Inappropriate prescribing of analgesics has a global impact on the health of elderly patients and the society. Empirical evidence on the prescription of analgesics among elderly Nigerians is scarce.
OBJECTIVES
The objective of the study was to evaluate the prescription pattern of analgesics and describe the co-prescribing of gastroprotective agents with non-steroidal anti-inflammatory drugs (NSAIDs) among elderly patients at the geriatric center, University College Hospital, Ibadan.
METHODS
A retrospective cross-sectional, hospital-based study was carried out among elderly patients (≥60 years) who were prescribed analgesics. Using a data extraction sheet, information on demographic characteristics, drug utilization pattern, and morbidities was obtained from patients' case files via electronic health records.
RESULTS
A total of 337 patients case files were reviewed, the mean age was 72 ± 8.8 years, and 210 (62.3%) were females. There were a total of 2074 medications prescribed, with 733 (35.3%) being analgesics. Majority of the elderly patients (259, 76.9%) were on nonopioids, with 252 (74.8%) on NSAIDs. Paracetamol was the most commonly prescribed analgesics (181, 24.6%), followed by diclofenac/misoprostol (177, 24.1%), opioid analgesic prescribed was 88 (12.0%), with paracetamol/codeine 58 (65.9%), and tramadol 16 (18.2%) being the most prescribed opioid. A significant proportion of the hypertensive elderly patients (160, 78.8%; P < 0.036) were on NSAIDs. The oral route of administration (302, 89.6%) was the most common route of administration. Majority (310, 92%) of elderly patients taking NSAIDs had a co-prescription for gastroprotective agents.
CONCLUSIONS
Majority of hypertensive patients were on NSAIDs. This calls for prompt awareness of rational analgesic use among the elderly to improve management and their survival.
背景
镇痛药的不适当处方对老年患者的健康和社会产生全球影响。关于尼日利亚老年人镇痛药处方的实证证据很少。
目的
本研究的目的是评估老年患者镇痛药的处方模式，并描述伊巴丹大学学院医院老年医学中心老年患者中胃保护剂与非甾体抗炎药（NSAIDs）的联合处方情况。
方法
对开具镇痛药的老年患者（≥60岁）进行了一项基于医院的回顾性横断面研究。使用数据提取表，通过电子健康记录从患者病历中获取有关人口统计学特征、药物使用模式和发病率的信息。
结果
共审查了337份患者病历，平均年龄为72±8.8岁，210名（62.3%）为女性。共开具了2074种药物，其中733种（35.3%）为镇痛药。大多数老年患者（259名，76.9%）使用非阿片类药物，252名（74.8%）使用NSAIDs。对乙酰氨基酚是最常用的镇痛药（181种，24.6%），其次是双氯芬酸/米索前列醇（177种，24.1%），开具的阿片类镇痛药为88种（12.0%），其中对乙酰氨基酚/可待因58种（65.9%）和曲马多16种（18.2%）是最常用的阿片类药物。很大一部分高血压老年患者（160名，78.8%；P<0.036）使用NSAIDs。口服给药途径（302种，89.6%）是最常见的给药途径。大多数服用NSAIDs的老年患者（310名，92%）同时开具了胃保护剂。
结论
大多数高血压患者使用NSAIDs。这需要提高老年人对合理使用镇痛药的认识，以改善治疗和提高生存率。
Zotero 插件