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治疗性低温在羊水栓塞管理中的应用。

The use of therapeutic hypothermia in the management of amniotic fluid embolism.

作者信息

Barriuso Valeria, Pombar Xavier, Bankowski Heather A

机构信息

Department of Obstetrics and Gynecology, Rush Medical Center, Chicago, IL, USA.

出版信息

Obstet Med. 2013 Jun;6(2):92-93. doi: 10.1258/OM.2011.110069. Epub 2013 May 3.

Abstract

BACKGROUND

Amniotic fluid embolism (AFE) is a rare peripartum obstetric emergency where patients seldom survive neurologically intact. The exact pathophysiology is not completely understood and treatment remains mainly supportive.

CASE

A 34-year-old African American woman gravida 1, para 0-0-0-0 at 38 weeks and four days induced for chronic hypertension with superimposed preeclampsia experienced an AFE during labour. Supportive treatment included early use of therapeutic hypothermia resulting in a normal neurological outcome.

CONCLUSION

This case demonstrates the timely use of therapeutic hypothermia in a patient surviving an AFE and suffering no neurological sequelae. Therapeutic hypothermia should be considered in the supportive treatment of AFE.

摘要

背景

羊水栓塞(AFE)是一种罕见的围产期产科急症,患者很少能在神经功能完好的情况下存活。确切的病理生理学尚未完全明确,治疗主要仍为支持性治疗。

病例

一名34岁的非裔美国女性,孕1产0,孕38周零4天,因慢性高血压合并子痫前期引产,分娩期间发生羊水栓塞。支持性治疗包括早期使用治疗性低温,结果患者神经功能恢复正常。

结论

本病例表明,治疗性低温可及时应用于羊水栓塞幸存者且无神经后遗症的患者。在羊水栓塞的支持性治疗中应考虑使用治疗性低温。

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引用本文的文献

本文引用的文献

1
Amniotic fluid embolism.羊水栓塞
Clin Obstet Gynecol. 2010 Jun;53(2):322-8. doi: 10.1097/GRF.0b013e3181e0ead2.
2
Incidence and risk factors for amniotic-fluid embolism.羊水栓塞的发生率和危险因素。
Obstet Gynecol. 2010 May;115(5):910-917. doi: 10.1097/AOG.0b013e3181d9f629.
4
Amniotic fluid embolism: an evidence-based review.羊水栓塞:一项基于证据的综述。
Am J Obstet Gynecol. 2009 Nov;201(5):445.e1-13. doi: 10.1016/j.ajog.2009.04.052.
5
Hypothermia for neuroprotection in adults after cardiopulmonary resuscitation.心肺复苏后成人低温神经保护治疗
Cochrane Database Syst Rev. 2009 Oct 7(4):CD004128. doi: 10.1002/14651858.CD004128.pub2.
10
Amniotic fluid embolism: analysis of the national registry.羊水栓塞:国家登记处分析
Am J Obstet Gynecol. 1995 Apr;172(4 Pt 1):1158-67; discussion 1167-9. doi: 10.1016/0002-9378(95)91474-9.

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