Clark Steven L
Women's and Children's Clinical Services, Clinical Services Group, Hospital Corporation of America, Nashville, Tennessee, USA.
Clin Obstet Gynecol. 2010 Jun;53(2):322-8. doi: 10.1097/GRF.0b013e3181e0ead2.
Amniotic fluid embolism (AFE) remains an enigmatic, but devastating obstetrical condition associated with significant maternal and newborn morbidity and mortality. Although our understanding of this condition is incomplete, research over the past 2 decades has altered traditional concepts of both the causation and pathophysiology of AFE. Although maternal treatment remains primarily supportive, prompt delivery of the fetus can substantially improve neonatal outcome after AFE-induced cardiac arrest. Newer biochemical markers may in the future enhance the specificity and sensitivity of this clinical diagnosis and could potentially lead to improved therapy.
羊水栓塞（AFE）仍然是一种神秘但具有毁灭性的产科病症，与孕产妇和新生儿的高发病率及死亡率相关。尽管我们对这种病症的了解并不全面，但过去20年的研究改变了关于AFE病因和病理生理学的传统观念。虽然孕产妇的治疗主要是支持性的，但在AFE导致心脏骤停后迅速娩出胎儿可显著改善新生儿结局。更新的生化标志物未来可能会提高这种临床诊断的特异性和敏感性，并有可能带来更好的治疗效果。
