Shahzad Hira, Ur-Rehman Sameer, Fatima Kulsoom, Sharif Nadia, Zubairi Ali Bin Sarwar
Section of Pulmonary and Critical Care Medicine, Department of Medicine, Aga Khan University, Stadium Road, Karachi 74800, Pakistan.
BMC Res Notes. 2013 Oct 1;6:394. doi: 10.1186/1756-0500-6-394.
Nodular lung disease is a rare presentation of sarcoidosis. Radiologically it can present as multiple pulmonary masses or solitary lung nodule.
We report three cases of nodular sarcoidosis in young females of Asian origin who had initially presented with dry cough and worsening dyspnea non-responsive to initially administered antibiotics. Pulmonary nodules were discovered upon radiographic imaging in all three cases which raised concern for the possibility of neoplastic processes. Subsequent biopsies revealed granulomatous inflammation indicative of sarcoidosis. All cases responded very well to systemic corticosteroids.
Sarcoidosis may present as nodular infiltrates which alerts the treating physician to other neoplastic and infectious diseases of the lungs. Appropriate workup may reveal the true nature of this disease and hence, simplify treatment.
结节性肺病是结节病的一种罕见表现形式。在放射学上，它可表现为多个肺部肿块或孤立性肺结节。
我们报告了3例亚洲裔年轻女性的结节性结节病病例，她们最初表现为干咳，呼吸困难进行性加重，最初使用抗生素治疗无效。所有3例患者经影像学检查均发现肺部结节，这引发了对肿瘤性病变可能性的担忧。随后的活检显示为肉芽肿性炎症，提示结节病。所有病例对全身使用糖皮质激素反应良好。
结节病可能表现为结节状浸润，这提醒治疗医生注意肺部的其他肿瘤性和感染性疾病。适当的检查可能揭示这种疾病的真实性质，从而简化治疗。
