Bellon E, Izbicki J R, Bockhorn M
Klinik und Poliklinik für Allgemein-, Viszeral und Thoraxchirurgie, Universitätsklinikum Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Deutschland.
Chirurg. 2017 Jan;88(1):18-24. doi: 10.1007/s00104-016-0303-1.
Chronic pancreatitis (CP) is an irreversible, inflammatory process, which is characterized by progressive fibrosis of the pancreas and leads to abdominal pain, endocrine and exocrine insufficiency. Surgical therapy is indicated by the absence of pain relief and local complications. The target of the surgical approach is to relieve the pancreatic and bile ducts and resection of the fibrotic and calcified parenchyma. Drainage procedures, such as the Partington-Rochelle method, are used in patients with isolated congestion of the pancreatic duct without further organ complications, such as inflammatory processes of the pancreatic head; however, patients with CP often have an inflammatory swelling of the pancreatic head. In this case classical pancreatoduodenectomy (PD) or organ-sparing duodenum-preserving pancreatic head resection (DPPHR) with its various techniques (e.g. Beger, Frey, Bern and V‑shape) can be applied. Due to similar long-term results PD should be carried out in cases of suspicion or detection of malignancies and DPPHR for treatment of CP.
慢性胰腺炎(CP)是一种不可逆的炎症过程,其特征为胰腺进行性纤维化,并导致腹痛、内分泌和外分泌功能不全。手术治疗适用于疼痛未缓解且存在局部并发症的情况。手术方法的目标是解除胰胆管梗阻并切除纤维化和钙化的实质组织。引流手术,如帕廷顿-罗谢尔法,适用于单纯胰管梗阻且无进一步器官并发症(如胰头部炎症)的患者;然而,CP患者常伴有胰头部炎性肿胀。在这种情况下,可采用经典的胰十二指肠切除术(PD)或保留器官的保留十二指肠胰头切除术(DPPHR)及其各种技术(如贝格尔、弗雷、伯恩和V形)。由于长期效果相似,PD适用于怀疑或检测到恶性肿瘤的情况,而DPPHR用于治疗CP。