Ambapkar Sachinkumar N, Shetty Naresh, Dwivedy Arpita
Associate Consultant, Dept. of Critical Care.
Consultant, Dept. of Medicine.
J Assoc Physicians India. 2016 Jul;64(7):93-94.
Rhabdomyolysis is syndrome characterized by muscle necrosis which causes the release of myoglobin into the bloodstream. The manifestations of this syndrome range from asymptomatic elevation of muscle enzymes to life-threatening cases associated with extremely high enzyme levels, electrolyte imbalance and acute renal failure. Symptoms of rhabdomyolysis include dark urine, muscle weakness and fatigue. Statins are the most commonly used drugs for prevention and management of dyslipidemia. We present an interesting case report on statin induced rhabdomyolysis with renal failure.
横纹肌溶解症是一种以肌肉坏死为特征的综合征,肌肉坏死会导致肌红蛋白释放到血液中。该综合征的表现范围从肌肉酶无症状升高到与极高酶水平、电解质失衡和急性肾衰竭相关的危及生命的病例。横纹肌溶解症的症状包括深色尿液、肌肉无力和疲劳。他汀类药物是预防和治疗血脂异常最常用的药物。我们报告一例关于他汀类药物引起的横纹肌溶解症伴肾衰竭的有趣病例。