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他汀类药物诱导的横纹肌溶解症

Statin-Induced Rhabdomyolysis.

作者信息

Ambapkar Sachinkumar N, Shetty Naresh, Dwivedy Arpita

机构信息

Associate Consultant, Dept. of Critical Care.

Consultant, Dept. of Medicine.

出版信息

J Assoc Physicians India. 2016 Jul;64(7):93-94.

PMID:27759359
Abstract

Rhabdomyolysis is syndrome characterized by muscle necrosis which causes the release of myoglobin into the bloodstream. The manifestations of this syndrome range from asymptomatic elevation of muscle enzymes to life-threatening cases associated with extremely high enzyme levels, electrolyte imbalance and acute renal failure. Symptoms of rhabdomyolysis include dark urine, muscle weakness and fatigue. Statins are the most commonly used drugs for prevention and management of dyslipidemia. We present an interesting case report on statin induced rhabdomyolysis with renal failure.

摘要

横纹肌溶解症是一种以肌肉坏死为特征的综合征,肌肉坏死会导致肌红蛋白释放到血液中。该综合征的表现范围从肌肉酶无症状升高到与极高酶水平、电解质失衡和急性肾衰竭相关的危及生命的病例。横纹肌溶解症的症状包括深色尿液、肌肉无力和疲劳。他汀类药物是预防和治疗血脂异常最常用的药物。我们报告一例关于他汀类药物引起的横纹肌溶解症伴肾衰竭的有趣病例。

相似文献

1
Statin-Induced Rhabdomyolysis.他汀类药物诱导的横纹肌溶解症
J Assoc Physicians India. 2016 Jul;64(7):93-94.
2
Statin-induced rhabdomyolysis in patient with renal failure and underlying undiagnosed hypothyroidism.他汀类药物诱导的横纹肌溶解症,发生于一名患有肾衰竭及潜在未确诊甲状腺功能减退症的患者。
Indian J Crit Care Med. 2016 May;20(5):305-7. doi: 10.4103/0972-5229.182210.
3
Delayed presentation of severe rhabdomyolysis leading to acute kidney injury following atorvastatin-gemfibrozil combination therapy: a case report.阿托伐他汀与吉非贝齐联合治疗后出现严重横纹肌溶解症并导致急性肾损伤的延迟表现:一例病例报告
J Med Case Rep. 2018 May 22;12(1):143. doi: 10.1186/s13256-018-1685-0.
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High-Intensity Atorvastatin-Induced Rhabdomyolysis in an Elderly Patient With NSTEMI: A Case Report and Review of the Literature.高强度阿托伐他汀致非ST段抬高型心肌梗死老年患者横纹肌溶解症:一例报告并文献复习
J Pharm Pract. 2017 Dec;30(6):658-662. doi: 10.1177/0897190016674109. Epub 2016 Oct 26.
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Rhabdomyolysis with concurrent atorvastatin and diltiazem.横纹肌溶解症合并阿托伐他汀与地尔硫䓬使用情况
Ann Pharmacother. 2002 Oct;36(10):1546-9. doi: 10.1345/aph.1A481.
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Rhabdomyolysis and AKI with Atorvastatin and Sitagliptin Use in the Setting of Low 25-Hydroxyvitamin D Levels.在 25-羟维生素 D 水平低的情况下使用阿托伐他汀和西他列汀导致横纹肌溶解和急性肾损伤。
J Gen Intern Med. 2017 Oct;32(10):1156-1159. doi: 10.1007/s11606-017-4115-x. Epub 2017 Jul 13.
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[Rhabdomyolysis and severe hepatotoxicity due to a drug-drug interaction between ritonavir and simvastatin. Could we use the most cost-effective statin in all human immunodeficiency virus-infected patients?].[利托那韦与辛伐他汀药物相互作用导致横纹肌溶解和严重肝毒性。我们能否在所有感染人类免疫缺陷病毒的患者中使用最具成本效益的他汀类药物?]
Enferm Infecc Microbiol Clin. 2014 Nov;32(9):579-82. doi: 10.1016/j.eimc.2014.03.014. Epub 2014 Jun 7.
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[Rhabdomyolysis following the coprescription of atorvastatin and fusidic acid].[阿托伐他汀与夫西地酸联合处方后发生的横纹肌溶解症]
Rev Med Interne. 2013 Jan;34(1):39-41. doi: 10.1016/j.revmed.2012.09.006. Epub 2012 Oct 24.
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Potential drug interaction between simvastatin and danazol causing rhabdomyolysis.辛伐他汀与达那唑之间可能存在药物相互作用,导致横纹肌溶解。
Can J Clin Pharmacol. 2003 Winter;10(4):172-4.
10
Rhabdomyolysis and HMG-CoA reductase inhibitors.横纹肌溶解症与HMG-CoA还原酶抑制剂
Ann Pharmacother. 2001 Sep;35(9):1096-107. doi: 10.1345/aph.10228.

引用本文的文献

1
Hypothyroidism-induced Rhabdomyolysis in a Pediatric Patient.一名儿科患者因甲状腺功能减退症诱发横纹肌溶解症。
JCEM Case Rep. 2024 Jul 30;2(8):luae118. doi: 10.1210/jcemcr/luae118. eCollection 2024 Aug.
2
Comparison of Lipid Profile, Liver Enzymes, Creatine Kinase and Lactate Dehydrogenase Among Type II Diabetes Mellitus Patients on Statin Therapy.他汀类药物治疗的2型糖尿病患者血脂谱、肝酶、肌酸激酶和乳酸脱氢酶的比较
Diabetes Metab Syndr Obes. 2020 Mar 18;13:763-773. doi: 10.2147/DMSO.S234382. eCollection 2020.