al-Eknah M M, Noakes D E
Br Vet J. 1989 Jul-Aug;145(4):328-36. doi: 10.1016/0007-1935(89)90030-4.
Uterine activity was monitored in three, 2-year-old nulliparous Ayrshire heifers using intrauterine balloon-tipped catheters and pressure transducers during the oestrous cycle, after ovariectomy and following the intravenous infusion of progesterone and oestradiol-17 beta. During the oestrous cycle uterine activity, as measured by the frequency and amplitude of contractions, was greatest around oestrus and declined during the luteal phase of the cycle; there was a close correlation with peripheral progesterone concentrations. In two animals after bilateral ovariectomy spontaneous uterine activity persisted, whilst in the third animal the uterus was quiescent. In the first two heifers intravenous progesterone infusions reduced the spontaneous uterine activity, eventually completely abolishing it. There was evidence of a dose response effect at the two infusion rates. Oestradiol benzoate infusions initially inhibited spontaneous uterine activity before stimulating contractions with some evidence of a dose relationship. As demonstrated in normal cyclical and steroid-infused animals, uterine activity appears to be under the influence of both hormones although the influence of progesterone is greater.
使用宫内带球囊导管和压力传感器，对三头2岁未孕的艾尔夏母牛在发情周期、卵巢切除术后以及静脉输注孕酮和雌二醇-17β后进行子宫活动监测。在发情周期中，通过收缩频率和幅度测量的子宫活动在发情期前后最为强烈，在周期的黄体期下降；与外周孕酮浓度密切相关。在两只动物双侧卵巢切除术后，子宫仍有自发活动，而在第三只动物中子宫处于静止状态。在前两头小母牛中，静脉输注孕酮降低了子宫的自发活动，最终完全消除了这种活动。在两种输注速率下有剂量反应效应的证据。苯甲酸雌二醇输注最初抑制子宫自发活动，然后刺激收缩，有一定剂量关系的证据。如在正常周期和输注类固醇的动物中所示，子宫活动似乎受两种激素的影响，尽管孕酮的影响更大。
