Qi Yafei, Ma Xiaoyuan, Li Gang, Ma Xiangxing, Wang Qing, Yu Dexin
Qilu Hospital of Shandong University, Jinan, Shandong Province, China.
Radiology Department, Jiaotong Hospital of Shandong Province, Jinan, Shandong Province, China.
PLoS One. 2016 Oct 19;11(10):e0164750. doi: 10.1371/journal.pone.0164750. eCollection 2016.
Conventional computed tomography (CT) approaches provides limited visualization of the entire endoluminal changes of aortic dissection (AD), which is essential for its treatment. As an important supplement, three-dimensional CT virtual intravascular endoscopy (VIE) can show relevant details. This study aims to determine the value of VIE in displaying the entry tear and intimal flap of AD.
Among 127 consecutive symptomatic patients with suspected AD who underwent CT angiography (CTA), 84 subjects were confirmed to have AD and were included in the study. Conventional CT and VIE images were observed and evaluated. From the 92 entry tears revealed via conventional CT, 88 (95.7%) tears appeared on VIE with round (n = 26), slit-shaped (n = 9), or irregular (n = 53) shapes, whereas the intimal flaps were sheetlike (n = 34), tubular (n = 34), wavelike (n = 13), or irregular (n = 7) in shape. The VIE also showed the spatial relationship between the torn flap and adjacent structures. Among 58 entry tears with multiple-line type flap shown on conventional CT, 41 (70.7%) appeared with an irregular shape on VIE, whereas among 30 tears with single-line type flap, 17 (56.7%) appeared as round or slit-shaped on VIE. These results demonstrated a significant difference (P < 0.05). The poor display of tears on VIE was related to the low CT attenuation values in lumen or in neighboring artifacts (P < 0.01).
CT VIE presents the complete configurations and details of the intimal tears and flaps of AD better than conventional CT approaches. Accordingly, it should be recommended as a necessary assessment tool for endovascular therapy and as part of strategy planning in pre-surgical patients.
传统计算机断层扫描(CT)方法对主动脉夹层(AD)整个腔内变化的可视化有限,而这对其治疗至关重要。作为重要补充,三维CT虚拟血管内内窥镜检查(VIE)可显示相关细节。本研究旨在确定VIE在显示AD入口撕裂和内膜瓣方面的价值。
在127例连续接受CT血管造影(CTA)检查的疑似AD有症状患者中,84例被确诊为AD并纳入研究。观察并评估传统CT和VIE图像。在传统CT显示的92处入口撕裂中,88处(95.7%)在VIE上显示,其形状为圆形(n = 26)、裂隙状(n = 9)或不规则形(n = 53),而内膜瓣的形状为片状(n = 34)、管状(n = 34)、波浪状(n = 13)或不规则形(n = 7)。VIE还显示了撕裂瓣与相邻结构之间的空间关系。在传统CT上显示为多线型瓣的58处入口撕裂中,41处(70.7%)在VIE上呈不规则形,而在30处显示为单线型瓣的撕裂中,17处(56.7%)在VIE上呈圆形或裂隙状。这些结果显示出显著差异(P < 0.05)。VIE上撕裂显示不佳与管腔内或相邻伪影的低CT衰减值有关(P < 0.01)。
CT VIE比传统CT方法能更好地呈现AD内膜撕裂和瓣的完整形态及细节。因此,应推荐其作为血管内治疗的必要评估工具以及术前患者策略规划的一部分。