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Genome-wide piggyBac transposon mediated screening reveals genes related to reprogramming.

作者信息

Zhang Xi, Wei Xinglin, Wu Yuanyuan, Wang Yuzhe, Tan Cheng, Hu Xiaoxiang, Li Ning, Capecchi Mario R, Wu Sen

机构信息

State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, 100193, China.

Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT, 84112, USA.

出版信息

Protein Cell. 2017 Feb;8(2):134-139. doi: 10.1007/s13238-016-0332-z.

DOI:10.1007/s13238-016-0332-z
PMID:27761808
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5291772/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d11/5291772/3c0d8c270ceb/13238_2016_332_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d11/5291772/b8057e315b11/13238_2016_332_Fig1a_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d11/5291772/3c0d8c270ceb/13238_2016_332_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d11/5291772/b8057e315b11/13238_2016_332_Fig1a_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d11/5291772/3c0d8c270ceb/13238_2016_332_Fig2_HTML.jpg

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本文引用的文献

1
The piggyBac Transposon as a Platform Technology for Somatic Cell Reprogramming Studies in Mouse.作为小鼠体细胞重编程研究平台技术的piggyBac转座子
Methods Mol Biol. 2016;1357:1-22. doi: 10.1007/7651_2015_274.
2
Efficient germ-line transmission obtained with transgene-free induced pluripotent stem cells.利用无转基因的诱导多能干细胞获得高效的种系传递。
Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10678-83. doi: 10.1073/pnas.1409933111. Epub 2014 Jul 7.
3
Molecular control of induced pluripotency.诱导多能性的分子调控
Cell Stem Cell. 2014 Jun 5;14(6):720-34. doi: 10.1016/j.stem.2014.05.002.
4
Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells.Cas9 效应因子介导的人类多能干细胞中的转录和分化调控。
Development. 2014 Jan;141(1):219-23. doi: 10.1242/dev.103341.
5
Suppression of malignancy by Smad3 in mouse embryonic stem cell formed teratoma.Smad3 在小鼠胚胎干细胞形成畸胎瘤中抑制恶性肿瘤。
Stem Cell Rev Rep. 2013 Oct;9(5):709-20. doi: 10.1007/s12015-013-9452-5.
6
Induction of pluripotency in mouse somatic cells with lineage specifiers.用谱系特异性蛋白诱导小鼠体细胞多能性。
Cell. 2013 May 23;153(5):963-75. doi: 10.1016/j.cell.2013.05.001.
7
From RNAi screens to molecular function in embryonic stem cells.从 RNAi 筛选到胚胎干细胞中的分子功能。
Stem Cell Rev Rep. 2012 Mar;8(1):32-42. doi: 10.1007/s12015-011-9269-z.
8
Genome-wide gain-of-function screen identifies novel regulators of pluripotency.全基因组功能获得性筛选鉴定多能性的新调控因子。
Stem Cells. 2010 Sep;28(9):1487-97. doi: 10.1002/stem.472.
9
Chromatin-Remodeling Components of the BAF Complex Facilitate Reprogramming.BAF 复合物的染色质重塑组件有助于重编程。
Cell. 2010 Jun 11;141(6):943-55. doi: 10.1016/j.cell.2010.04.037.
10
Chromosomal transposition of PiggyBac in mouse embryonic stem cells.PiggyBac在小鼠胚胎干细胞中的染色体转座。
Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9290-5. doi: 10.1073/pnas.0801017105. Epub 2008 Jun 25.