Normann Richard A, Fernandez Eduardo
Departments of Bioengineering and Ophthalmology, University of Utah, Salt Lake City, UT 84112, USA.
J Neural Eng. 2016 Dec;13(6):061003. doi: 10.1088/1741-2560/13/6/061003. Epub 2016 Oct 20.
This paper briefly describes some of the recent progress in the development of penetrating microelectrode arrays and highlights the use of two of these devices, Utah electrode arrays and Utah slanted electrode arrays, in two therapeutic interventions: recording volitional skeletal motor commands from the central nervous system, and recording motor commands and evoking somatosensory percepts in the peripheral nervous system (PNS). The paper also briefly explores other potential sites for microelectrode array interventions that could be profitably pursued and that could have important consequences in enhancing the quality of life of patients that has been compromised by disorders of the central and PNSs.
本文简要介绍了穿透式微电极阵列开发方面的一些最新进展，并重点介绍了其中两种设备——犹他电极阵列和犹他倾斜电极阵列——在两种治疗干预中的应用：记录来自中枢神经系统的自主骨骼运动指令，以及记录外周神经系统（PNS）中的运动指令并诱发躯体感觉。本文还简要探讨了微电极阵列干预的其他潜在部位，这些部位值得深入研究，并且可能对改善因中枢和外周神经系统疾病而生活质量受损的患者的生活质量产生重要影响。
