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Carboplatin-allergic patients undergoing desensitization: prevalence and impact of the BRCA 1/2 mutation.

作者信息

Galvão Violeta Régnier, Phillips Elizabeth, Giavina-Bianchi Pedro, Castells Mariana C

机构信息

Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital, Boston, Mass; Division of Clinical Immunology and Allergy, University of São Paulo Medical School, São Paulo, Brazil.

Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Tenn; Institute for Immunology and Infectious diseases, Murdoch University, Perth, Australia.

出版信息

J Allergy Clin Immunol Pract. 2017 May-Jun;5(3):816-818. doi: 10.1016/j.jaip.2016.08.012. Epub 2016 Oct 17.

DOI:10.1016/j.jaip.2016.08.012
PMID:27765459
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5393958/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60b3/5393958/44ad25c72562/nihms824990f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60b3/5393958/cfcc6784d73d/nihms824990f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60b3/5393958/44ad25c72562/nihms824990f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60b3/5393958/cfcc6784d73d/nihms824990f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60b3/5393958/44ad25c72562/nihms824990f2.jpg

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本文引用的文献

1
Frequency of Germline Mutations in 25 Cancer Susceptibility Genes in a Sequential Series of Patients With Breast Cancer.一系列乳腺癌患者中25个癌症易感基因的胚系突变频率
J Clin Oncol. 2016 May 1;34(13):1460-8. doi: 10.1200/JCO.2015.65.0747. Epub 2016 Mar 14.
2
Safety, Costs, and Efficacy of Rapid Drug Desensitizations to Chemotherapy and Monoclonal Antibodies.快速药物脱敏治疗化疗和单克隆抗体的安全性、成本和疗效。
J Allergy Clin Immunol Pract. 2016 May-Jun;4(3):497-504. doi: 10.1016/j.jaip.2015.12.019. Epub 2016 Feb 16.
3
Deciphering the BRCA1 Tumor Suppressor Network.解析BRCA1肿瘤抑制网络。
J Biol Chem. 2015 Jul 17;290(29):17724-17732. doi: 10.1074/jbc.R115.667931. Epub 2015 Jun 5.
4
Hypersensitivity to biological agents-updated diagnosis, management, and treatment.生物制剂超敏反应——最新诊断、管理与治疗
J Allergy Clin Immunol Pract. 2015 Mar-Apr;3(2):175-85; quiz 186. doi: 10.1016/j.jaip.2014.12.006.
5
Deleterious BRCA1/2 mutation is an independent risk factor for carboplatin hypersensitivity reactions.有害的 BRCA1/2 突变是卡铂过敏反应的独立危险因素。
Br J Cancer. 2013 Aug 20;109(4):1072-8. doi: 10.1038/bjc.2013.389. Epub 2013 Jul 18.
6
Integrated genomic analyses of ovarian carcinoma.卵巢癌的综合基因组分析。
Nature. 2011 Jun 29;474(7353):609-15. doi: 10.1038/nature10166.
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BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases.BRCA1和BRCA2基因突变在卵巢癌病例中占很大比例。
Cancer. 2005 Dec 15;104(12):2807-16. doi: 10.1002/cncr.21536.
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Tryptase, a mediator of human mast cells.
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