Joseph Paule V, Abey Sarah K, Henderson Wendy A
National Institutes of Health.
Oncol Nurs Forum. 2016 Nov 1;43(6):784-788. doi: 10.1188/16.ONF.784-788.
Nutrition is a factor involved in inflammation and a modulator of risk toward some cancers, and the complexity of linkages between dietary components and epigenetics mechanisms (e.g., DNA methylation, histone modification, chromatin remodeling) may affect the inflammation phenotype and the development of cancer. An increasing number of studies support the role of diet in cancer development, prevention, and treatment. Although current knowledge regarding nutri-epigenetics is expanding, more work is needed, and nurse scientists have the potential to significantly contribute to the expansion of this knowledge.
营养是炎症相关因素以及某些癌症风险的调节因子，饮食成分与表观遗传机制（如DNA甲基化、组蛋白修饰、染色质重塑）之间联系的复杂性可能会影响炎症表型和癌症发展。越来越多的研究支持饮食在癌症发展、预防和治疗中的作用。尽管目前关于营养表观遗传学的知识在不断扩展，但仍需要开展更多工作，而护士科学家有潜力为这一知识领域的拓展做出重大贡献。
