绿茶及其成分通过调节细胞信号通路在癌症预防中的意义。
Implications of Green Tea and Its Constituents in the Prevention of Cancer via the Modulation of Cell Signalling Pathway.
作者信息
Rahmani Arshad H, Al Shabrmi Fahad M, Allemailem Khaled S, Aly Salah M, Khan Masood A
机构信息
Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraidah 6699, Saudi Arabia.
Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraidah 6699, Saudi Arabia ; Department of Pathology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt.
出版信息
Biomed Res Int. 2015;2015:925640. doi: 10.1155/2015/925640. Epub 2015 Apr 21.
Green tea is commonly used as a beverage worldwide, especially in China, Japan, Morocco, and Saudi Arabia. Green tea and its constituents have been considered very effective in the prevention and treatment of various diseases. It contains a variety of catechins, which show a pivotal role in the modulation of biological activities and also act as chemopreventive agents. Earlier studies have confirmed that green tea and its chief constituent epigallocatechin gallate (EGCG) have a potential role in the management of cancer through the modulation of cell signaling pathways. In this review, we focused on the beneficial effects of green tea and its constituents in the cancer prevention and treatment and its impact on modulation of molecular pathways.
绿茶在全球范围内普遍作为一种饮品使用，尤其在中国、日本、摩洛哥和沙特阿拉伯。绿茶及其成分被认为在预防和治疗各种疾病方面非常有效。它含有多种儿茶素，这些儿茶素在调节生物活性中发挥关键作用，并且还充当化学预防剂。早期研究已证实，绿茶及其主要成分表没食子儿茶素没食子酸酯（EGCG）通过调节细胞信号通路在癌症管理中具有潜在作用。在本综述中，我们聚焦于绿茶及其成分在癌症预防和治疗中的有益作用及其对分子途径调节的影响。
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