Guilleminault C, Quera-Salva M A, Powell N B, Riley R W
Stanford University School of Medicine, Palo Alto, California.
Eur Respir J. 1989 Jul;2(7):604-12.
Many therapeutic approaches, including mandibular surgery, have been proposed for the treatment of obstructive sleep apnoea syndrome. In the largest study of its type yet reported, 54 patients (population A) underwent mandibular surgery: 36 had palato-pharyngoplasty and inferior sagittal osteotomy of the mandible with hyoid myotomy and resuspension, and 18 (population B) had maxillo-mandibular hyoid advancement, a procedure consisting of palato-pharyngoplasty, inferior sagittal osteotomy of the mandible with hyoid myotomy and, several months later, a maxillo-mandibular osteotomy. Criteria for procedure selection and for evaluation of results were pre-set, and clinical and polygraphic follow-up occurred 6-8 months after final surgery. In population A, 32 of the 36 patients had improved; but only 20 were evaluated as "satisfactory". In contrast, all of the population B patients were judged satisfactory. Four of the population B patients received nasal continuous positive airway pressure (CPAP) before any surgery, and both approaches gave similar good polygraphic results. The degree of skeletal cranio-facial deficiencies, particularly retrognathia, is crucial for procedure selection. We describe potential procedural risks and problems.
许多治疗方法,包括下颌手术,已被提出用于治疗阻塞性睡眠呼吸暂停综合征。在该类型迄今为止规模最大的研究中,54例患者(A组)接受了下颌手术:36例进行了腭咽成形术、下颌骨矢状下截骨术并联合舌骨肌切开术和舌骨重新悬吊术,18例(B组)进行了上颌-下颌-舌骨前移术,该手术包括腭咽成形术、下颌骨矢状下截骨术并联合舌骨肌切开术,数月后再进行上颌-下颌截骨术。预先设定了手术选择标准和结果评估标准,最终手术后6至8个月进行临床和多导睡眠监测随访。A组36例患者中有32例病情改善;但只有20例被评估为“满意”。相比之下,B组所有患者均被判定为满意。B组中有4例患者在任何手术前接受了鼻持续气道正压通气(CPAP)治疗,两种方法均产生了相似的良好多导睡眠监测结果。骨骼颅面缺陷程度,尤其是下颌后缩,对于手术选择至关重要。我们描述了潜在的手术风险和问题。