Guilleminault C, Stoohs R
Stanford University School of Medicine, Palo Alto, California.
Lung. 1990;168 Suppl:912-9. doi: 10.1007/BF02718227.
Increased upper airway resistance during sleep may lead to heavy snoring and/or obstructive sleep apnea in infants and children. Clinical symptoms will be seen with increased upper airway resistance during sleep, even without obstructive sleep apnea or significant oxygen saturation drop. It may be responsible for apparent life threatening events (ALTE). Mild cranio-facial morphometric changes are often associated with increased upper airway resistance during sleep, and there is a continuous interaction between airway patency during sleep and maxillo-mandibular growth. Nasal CPAP can be as much a diagnostic tool as a treatment procedure. Orthodontic and surgical approaches may also be combined in the treatment of this significant health problem.
睡眠期间上呼吸道阻力增加可能导致婴幼儿出现严重打鼾和/或阻塞性睡眠呼吸暂停。即使没有阻塞性睡眠呼吸暂停或明显的血氧饱和度下降,睡眠期间上呼吸道阻力增加也会出现临床症状。这可能是导致明显危及生命事件(ALTE)的原因。轻度颅面形态学改变常与睡眠期间上呼吸道阻力增加有关,并且睡眠期间气道通畅与上颌下颌生长之间存在持续相互作用。鼻持续气道正压通气(CPAP)既可以作为一种诊断工具,也可以作为一种治疗手段。正畸和手术方法也可联合用于治疗这一重大健康问题。