精囊：滋养层淋巴细胞交叉反应抗原的一个来源。
Seminal vesicles: a source of trophoblast lymphocyte cross-reactive antigen.
作者信息
Thaler C J, Critser J K, McIntyre J A, Faulk W P
机构信息
Center for Reproduction and Transplantation Immunology, Methodist Hospital of Indiana, Indianapolis, 46202.
出版信息
Fertil Steril. 1989 Sep;52(3):463-8. doi: 10.1016/s0015-0282(16)60920-2.
Maternal recognition of allotypic trophoblast lymphocyte cross-reactive (TLX) antigens is proposed to be involved in immunologic acceptance of the allogeneic fetus. The presence of TLX antigens in seminal plasma suggests that sensitization can occur before fertilization and implantation. In this study, the origin of TLX antigens within the male reproductive tract was investigated. Analysis of split ejaculates and immunohistological examinations of male accessory gland tissues showed the luminal epithelium of seminal vesicles as the source of seminal plasma TLX antigens. This finding suggests that seminal vesicles may play a role in the immunology of human reproduction.
母体能识别同种异型滋养层淋巴细胞交叉反应（TLX）抗原，这一过程被认为与对同种异体胎儿的免疫接受有关。精浆中存在TLX抗原表明，致敏可能在受精和着床之前就已发生。在本研究中，对雄性生殖道内TLX抗原的来源进行了调查。对分段射精的分析以及对雄性附属腺组织的免疫组织学检查显示，精囊的腔上皮是精浆TLX抗原的来源。这一发现表明，精囊可能在人类生殖免疫学中发挥作用。
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