Suriya J, Bharathiraja S, Krishnan M, Manivasagan P, Kim S-K
School of Environmental Sciences, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India.
CAS in Marine Biology, Annamalai University, Porto Novo, Tamil Nadu, India.
Adv Food Nutr Res. 2016;79:43-66. doi: 10.1016/bs.afnr.2016.08.001. Epub 2016 Sep 3.
Marine microorganisms that have the possibility to survive in diverse conditions such as extreme temperature, pH, pressure, and salinity are known as extremophiles. They produce biocatalysts so named as extremozymes that are active and stable at extreme conditions. These enzymes have numerous industrial applications due to its distinct properties. Till now, only a fraction of microorganisms on Earth have been exploited for screening of extremozymes. Novel techniques used for the cultivation and production of extremophiles, as well as cloning and overexpression of their genes in various expression systems, will pave the way to use these enzymes for chemical, food, pharmaceutical, and other industrial applications.
有可能在极端温度、pH值、压力和盐度等各种条件下生存的海洋微生物被称为极端微生物。它们产生的生物催化剂被称为极端酶,在极端条件下具有活性且稳定。由于这些酶具有独特的性质,因此有许多工业应用。到目前为止,地球上只有一小部分微生物被用于筛选极端酶。用于培养和生产极端微生物的新技术,以及在各种表达系统中克隆和过表达它们的基因,将为这些酶在化学、食品、制药和其他工业应用中的使用铺平道路。