非久坐生活方式可降低老年白人成年人髋部骨折风险：基督复临安息日会健康研究-2
Non-sedentary Lifestyle Can Reduce Hip Fracture Risk among Older Caucasians Adults: The Adventist Health Study-2.
作者信息
Lousuebsakul-Matthews Vichuda, Thorpe Donna, Knutsen Raymond, Beeson W Larry, Fraser Gary E, Knutsen Synnove F
机构信息
Center for Nutrition, Healthy Lifestyle and Disease Prevention, School of Public Health, Loma Linda University, Loma Linda, CA, USA; Department of Health Services, Los Angeles, CA, USA.
Department of Physical Therapy, School of Allied Health Professions, Loma Linda University, Loma Linda, CA, USA.
出版信息
Br J Med Med Res. 2015;8(3):220-229. doi: 10.9734/BJMMR/2015/17685. Epub 2015 Apr 27.
AIMS
The beneficial effect of physical activity on reducing hip fracture risk has been supported in many previous studies. The present cohort study explores the relationship between total daily physical activity expressed as MET-hour/day and hip fracture risk among men over 50 years of age and postmenopausal women (n=22,836).
METHODOLOGY
Associations between self-reported hip fracture incidence and total daily physical activity and selected lifestyle factors were assessed using Cox proportional hazard regression.
RESULTS
In gender-specific multivariable models, total activity above average (≥ 51 MET-hours per day for men, ≥ 48 MET-hours per day for women) compared to those with sedentary lifestyle (< 40 MET-hours per day) reduced the risk of hip fracture by 60% among men (HR=0.40, 95%CI: 0.23-0.70) (Ptrend=0.002) and 48% among women (HR=0.52, 95%CI: 0.32-0.84) (Ptrend=0.01).
CONCLUSION
Our findings suggest that a moderate level of physical activity and avoiding a sedentary lifestyle can reduce the risk of hip fracture among the elderly.
目的
以往许多研究都证实了体育活动对降低髋部骨折风险具有有益作用。本队列研究探讨了以每日代谢当量小时数（MET-小时/天）表示的每日总体育活动量与50岁以上男性及绝经后女性（n = 22,836）髋部骨折风险之间的关系。
方法
使用Cox比例风险回归评估自我报告的髋部骨折发病率与每日总体育活动量及选定生活方式因素之间的关联。
结果
在按性别划分的多变量模型中，与久坐不动的生活方式（每天<40代谢当量小时）的人相比，总活动量高于平均水平（男性≥51代谢当量小时/天，女性≥48代谢当量小时/天）的男性髋部骨折风险降低了60%（风险比[HR]=0.40，95%置信区间[CI]：0.23 - 0.70）（趋势P值=0.002），女性降低了48%（HR = 0.52，95%CI：0.32 - 0.84）（趋势P值=0.01）。
结论
我们的研究结果表明，适度的体育活动和避免久坐不动的生活方式可降低老年人髋部骨折的风险。
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