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韩国骨质疏松性椎体压缩骨折的发病率及治疗趋势:一项基于全国人口的研究

Incidence and Management Trends of Osteoporotic Vertebral Compression Fractures in South Korea: A Nationwide Population-Based Study.

作者信息

Choi Sung Hoon, Kim Dong-Yun, Koo Ja Wook, Lee Seung Gun, Jeong Soo-Young, Kang Chang-Nam

机构信息

Department of Orthopedic Surgery, Hanyang University College of Medicine, Seoul, Korea.

出版信息

Asian Spine J. 2020 Apr;14(2):220-228. doi: 10.31616/asj.2019.0051. Epub 2019 Nov 1.

Abstract

STUDY DESIGN

A nationwide population-based study.

PURPOSE

Osteoporotic vertebral compression fracture (OVCF) is a major public health issue. This study examined the incidence and management trends of OVCF in South Korea.

OVERVIEW OF LITERATURE

The incidence rates, management trends, and patterns of OVCF differ in different parts of the world. The age-standardized OVCF incidence rate in 2015 was higher in the United States and Asia than in Europe.

METHODS

A nationwide database (2012-2016) acquired from the Korean Health Insurance Review and Assessment Service was analyzed. International disease categories in the 10th revision of the International Statistical Classification of Diseases and Related Health Problems codes, medical procedure codes, and examination codes were used to identify and sort OVCF patients aged >50 years.

RESULTS

There were 644,500 OVCF cases from 2012 to 2016. OVCF was most common in patients in their seventies (45%) and the number of patients increased from 117,361 in 2012 to 139,889 in 2016 (p <0.001). During 2012-2016, 8.9% of patients visited the emergency department; of those, 54.3% were hospitalized and 35% underwent magnetic resonance imaging. In OVCF treatment, bone cement augmentation rates increased from 23.4% in 2012 to 25.2% in 2016 (p <0.001), while conservative treatment rates slightly decreased from 76.5% in 2012 to 74.7% in 2016 (p <0.001). The total health insurance cost was $193,210,353.55 in 2012 and $281,968,877.65 in 2016.

CONCLUSIONS

The 5-year incidence of OVCF per 100,000 persons was 852.24 cases, and 45% of OVCF in South Korea occurred in patients in their seventies. The bone cement augmentation rate and total cost of OVCF are continuously increasing.

摘要

研究设计

一项基于全国人口的研究。

目的

骨质疏松性椎体压缩骨折(OVCF)是一个重大的公共卫生问题。本研究调查了韩国OVCF的发病率及治疗趋势。

文献综述

OVCF的发病率、治疗趋势及模式在世界不同地区有所不同。2015年,美国和亚洲的年龄标准化OVCF发病率高于欧洲。

方法

分析从韩国健康保险审查与评估服务机构获取的全国性数据库(2012 - 2016年)。使用《国际疾病分类及相关健康问题统计分类》第10版中的国际疾病类别代码、医疗程序代码和检查代码来识别和分类年龄大于50岁的OVCF患者。

结果

2012年至2016年共有644,500例OVCF病例。OVCF在七十多岁的患者中最为常见(45%),患者数量从2012年的117,361例增加到2016年的139,889例(p <0.001)。在2012 - 2016年期间,8.9%的患者前往急诊科就诊;其中,54.3%住院治疗,35%接受了磁共振成像检查。在OVCF治疗中,骨水泥强化率从2012年的23.4%上升至2016年的25.2%(p <0.001),而保守治疗率从2012年的76.5%略有下降至2016年的74.7%(p <0.001)。2012年的医保总费用为193,210,353.55美元,2016年为281,968,877.65美元。

结论

每10万人中OVCF的5年发病率为852.24例,韩国45%的OVCF发生在七十多岁的患者中。OVCF的骨水泥强化率和总费用持续上升。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da3c/7113475/99bbc4bbbbec/asj-2019-0051f1.jpg

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